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From The Labs

Solving the mystery of NPM1 in acute myeloid leukemia

November 13, 2018 leukemia,  NPM1,  Research

Although it has long been recognized that mutations of gene NPM1 play an important role in acute myeloid leukemia, no one has determined how the normal

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From The Labs

Sample size matters in multisensory integration studies

November 8, 2018 accuracy,  McGurk effect,  multisensory integration,  reproducibility,  Research,  sample size

The accuracy and reproducibility of research studies are a major concern of the scientific community. At Baylor College of Medicine, Dr. Michael Beauchamp and Dr.

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From The Labs

Tracking down microRNA candidates that can contribute to disease

November 6, 2018 ADmiRE,  Cancer,  developmental disease,  gnomAD,  heart disease,  microRNA,  The Cancer Genome Atlas,  whole exome sequencing

What started as Ninad Oak’s side project turned out into something much larger, his doctorate thesis. “The project started as my qualifying exam that I

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From The Labs

Image of the Month: Snapshot of eye development in the fruit fly

November 1, 2018 congenital bilateral cataracts,  DNMBP,  Drosophila,  fruit fly,  Research

In his lab at Baylor College of Medicine, Dr. Hugo Bellen and his colleagues work with the fruit fly, Drosophila melanogaster, as a model system

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From The Labs

Preventing sudden cardiac death with genome editing

October 30, 2018 cardiomyocytes,  catecholaminergic polymorphic ventricular tachycardia,  CRISPR/Cas9,  inherited cardiac arrhythmia disorders,  R176Q,  Research,  RyR2,  sudden cardiac death

Each year, at least 3 million people worldwide die of sudden cardiac death. In the U.S., this number reaches up to 450,000 people. Although sudden

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From The Labs

Estrogen receptor can affect resistance to endocrine therapy and metastasis in breast cancer

October 25, 2018 Breast Cancer,  ESR1,  estrogen receptor-positive,  Metastasis,  Research,  resistance to endocrine therapy

Resistance to therapy is common in estrogen receptor positive (ER+) breast cancer, the most common type of breast cancer, and eventual development of metastatic disease

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From The Labs

INSiGHT into neural fate in the retina

October 23, 2018 INSiGHT,  neural development,  Research,  retina,  retinal regulators,  Slc44a1,  vasculature in the retina

Vision begins in the retina, a light-sensing neural network in the eye that is critical for our ability observe the world around us. “Unless we

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From The Labs

UPDATE: The dark side of antibiotic ciprofloxacin

October 18, 2018 antibiotic,  aortic aneurysms and dissections,  ciprofloxacin,  fluoroquinolones,  PRAC,  product warning,  Research,  vascular endothelium

In July 2018, From the Labs released a post on the laboratory evidence suggesting that in a mouse model of moderately stressed aortas, exposure to

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From The Labs

Mom and dad genes and the intricate process of gene regulation

October 16, 2018 DNA methylation,  epigenome,  gene regulation,  genome,  Research,  SD-ASM,  WGBS

If the genome is like computer hardware, then the epigenome is the software that turns certain genes on and others off. During development, the epigenome

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From The Labs

McNair Scholar Spotlight: Dr. Xiang “Shawn” Zhang

October 11, 2018 bone metastasis,  Breast Cancer,  McNair scholar,  Research

From the Labs sat down with McNair Scholar Dr. Xiang “Shawn” Zhang to learn more about him, his research, his motivations to pursue a career

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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