DNA methylation Archives - Baylor College of Medicine Blog Network

The researchers report the development of a chemical-based sequencing method to quantify different epigenetic markers simultaneously.

From The Labs

Tuberculosis induces premature cellular aging

March 24, 2022March 24, 2022cellular aging, DNA methylation, epigenetic clock, epigenetics, Research, TB, tuberculosis

It’s possible that premature cellular aging in TB is one reason why survivors have a three-fold increased risk of mortality.

From The Labs

Sorting out cell type-specific molecular barcodes

July 14, 2020August 11, 2020CluBCpG, DNA methylation, epigenetics, PReLIM, Research, WGBS

Researchers at Baylor College of Medicine developed novel software that can distinguish methylation patterns within bulk WGBS data.

From The Labs

A closer look at severe malnutrition

February 11, 2020February 11, 2020DNA methylation, epigenetics, ESAM, malnutrition, NESAM, Research

More than two million children die worldwide each year of severe malnutrition. Severe acute childhood malnutrition presents in two clinically distinct forms: edematous severe acute

From The Labs

The making of a ‘couch potato mouse’

December 30, 2019December 30, 2019AgRP neurons, couch potato, DNA methylation, epigenetics, Exercise, hypothalamus, overnutrition, Research

Some people love to exercise, but others hate it. Many researchers consider genetics to be the reason for a person’s inclination to exercise, or not

From The Labs

Rearranging genomic structure rewires gene control in cancer

November 14, 2019November 14, 2019Cancer, cancer genetics, Cancer Genome Atlas, DNA methylation, epigenetics, genomic structural variation, immune infiltration, Research

Widespread DNA damage is common in the cancer genome. Understanding the mechanisms that lead to it is of great interest to cancer physicians and scientists

From The Labs

Image of the Month: Islet of Langerhans

October 1, 2019October 2, 2019Diabetes, DNA methylation, epigenetics, insulin, Islet of Langerhans, overnutrition, Research

Cells of the Islets of Langerhans in the pancreas help regulate blood sugar. Disrupting their normal function can contribute to the development of diabetes. The

From The Labs

Early postnatal overnutrition sets the body on a fast track to aging

September 19, 2019September 26, 2019Aging, Diabetes, DNA methylation, infancy, Obesity, overnutrition, Research

Overnutrition during early infancy can have adverse health consequences later in life. Although researchers have known this for quite some time, the explanations have been

From The Labs

This map facilitates the search for epigenetic causes of disease

June 6, 2019June 7, 2019CoRSIV, DNA methylation, epigenetics, genome, Homa Shalchi, Research

More than 15 years after scientists first mapped the human genome, most diseases still cannot be predicted based on one’s genes. Thus, researchers also are

From The Labs

Mom and dad genes and the intricate process of gene regulation

October 16, 2018October 16, 2018DNA methylation, epigenome, gene regulation, genome, Research, SD-ASM, WGBS

If the genome is like computer hardware, then the epigenome is the software that turns certain genes on and others off. During development, the epigenome