DNA methylation Archives - Baylor College of Medicine Blog Network

A doctor, seen from the neck down, writing on paper while talking to another person.

The findings bring hope and direction to better understand this emerging condition and support continuing these studies.

From The Labs

Changes in gene p16 create a permissive microenvironment for colon cancer growth

May 25, 2023 APC gene, Colorectal Cancer, DNA methylation, epimutation, p16, polyps, Research, tumor microenvironment

The researchers also developed a strategy that reduced tumor growth and improved survival in tumor-bearing mice.

From The Labs

Breakthrough epigenetic study can improve the power to predict disease risk

January 31, 2023 CoRSIVs, disease risk, DNA methylation, epigenetics, epigenome-wide association study, EWAS, Research

The researchers hope their approach will have transformative effects in the field of epigenetic epidemiology.

From The Labs

New method boosts the study of regulation of gene activity

June 30, 2022 DNA methylation, epigenetics, method, NT-seq, Research

The researchers report the development of a chemical-based sequencing method to quantify different epigenetic markers simultaneously.

From The Labs

Tuberculosis induces premature cellular aging

March 24, 2022 cellular aging, DNA methylation, epigenetic clock, epigenetics, Research, TB, tuberculosis

It’s possible that premature cellular aging in TB is one reason why survivors have a three-fold increased risk of mortality.

From The Labs

Sorting out cell type-specific molecular barcodes

July 14, 2020 CluBCpG, DNA methylation, epigenetics, PReLIM, Research, WGBS

Researchers at Baylor College of Medicine developed novel software that can distinguish methylation patterns within bulk WGBS data.

From The Labs

A closer look at severe malnutrition

February 11, 2020 DNA methylation, epigenetics, ESAM, malnutrition, NESAM, Research

More than two million children die worldwide each year of severe malnutrition. Severe acute childhood malnutrition presents in two clinically distinct forms: edematous severe acute

From The Labs

The making of a ‘couch potato mouse’

December 30, 2019 AgRP neurons, couch potato, DNA methylation, epigenetics, Exercise, hypothalamus, overnutrition, Research

Some people love to exercise, but others hate it. Many researchers consider genetics to be the reason for a person’s inclination to exercise, or not

From The Labs

Rearranging genomic structure rewires gene control in cancer

November 14, 2019 Cancer, cancer genetics, Cancer Genome Atlas, DNA methylation, epigenetics, genomic structural variation, immune infiltration, Research

Widespread DNA damage is common in the cancer genome. Understanding the mechanisms that lead to it is of great interest to cancer physicians and scientists

From The Labs

Image of the Month: Islet of Langerhans

October 1, 2019 Diabetes, DNA methylation, epigenetics, insulin, Islet of Langerhans, overnutrition, Research

Cells of the Islets of Langerhans in the pancreas help regulate blood sugar. Disrupting their normal function can contribute to the development of diabetes. The

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