Tuberculosis induces premature cellular aging
It’s possible that premature cellular aging in TB is one reason why survivors have a three-fold increased risk of mortality.
Read more
DNA methylation
Sorting out cell type-specific molecular barcodes
Researchers at Baylor College of Medicine developed novel software that can distinguish methylation patterns within bulk WGBS data.
Read more
A closer look at severe malnutrition
More than two million children die worldwide each year of severe malnutrition. Severe acute childhood malnutrition presents in two clinically distinct forms: edematous severe acute
Read more
The making of a ‘couch potato mouse’
Some people love to exercise, but others hate it. Many researchers consider genetics to be the reason for a person’s inclination to exercise, or not
Read more
Rearranging genomic structure rewires gene control in cancer
Widespread DNA damage is common in the cancer genome. Understanding the mechanisms that lead to it is of great interest to cancer physicians and scientists
Read more
Image of the Month: Islet of Langerhans
Cells of the Islets of Langerhans in the pancreas help regulate blood sugar. Disrupting their normal function can contribute to the development of diabetes. The
Read more
Early postnatal overnutrition sets the body on a fast track to aging
Overnutrition during early infancy can have adverse health consequences later in life. Although researchers have known this for quite some time, the explanations have been
Read more
This map facilitates the search for epigenetic causes of disease
More than 15 years after scientists first mapped the human genome, most diseases still cannot be predicted based on one’s genes. Thus, researchers also are
Read more
Mom and dad genes and the intricate process of gene regulation
If the genome is like computer hardware, then the epigenome is the software that turns certain genes on and others off. During development, the epigenome
Read more