Sorting out cell type-specific molecular barcodes
In the last 10 years, scientists generated thousands of whole genome bisulfite sequencing (WGBS) data sets costing millions of dollars, yet were unable to appreciate
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DNA methylation
A closer look at severe malnutrition
More than two million children die worldwide each year of severe malnutrition. Severe acute childhood malnutrition presents in two clinically distinct forms: edematous severe acute
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The making of a ‘couch potato mouse’
Some people love to exercise, but others hate it. Many researchers consider genetics to be the reason for a person’s inclination to exercise, or not
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Rearranging genomic structure rewires gene control in cancer
Widespread DNA damage is common in the cancer genome. Understanding the mechanisms that lead to it is of great interest to cancer physicians and scientists
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Image of the Month: Islet of Langerhans
Cells of the Islets of Langerhans in the pancreas help regulate blood sugar. Disrupting their normal function can contribute to the development of diabetes. The
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Early postnatal overnutrition sets the body on a fast track to aging
Overnutrition during early infancy can have adverse health consequences later in life. Although researchers have known this for quite some time, the explanations have been
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This map facilitates the search for epigenetic causes of disease
More than 15 years after scientists first mapped the human genome, most diseases still cannot be predicted based on one’s genes. Thus, researchers also are
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Mom and dad genes and the intricate process of gene regulation
If the genome is like computer hardware, then the epigenome is the software that turns certain genes on and others off. During development, the epigenome
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