A novel source of genetic variation influencing childhood brain tumors
The researchers hope their findings will lead to improved tools for identifying children at risk or tailoring therapies to individual genetic profiles.
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DNA methylation
Uncovering unique features of early onset colorectal cancer in racial and ethnic minorities
The findings bring hope and direction to better understand this emerging condition and support continuing these studies.
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Changes in gene p16 create a permissive microenvironment for colon cancer growth
The researchers also developed a strategy that reduced tumor growth and improved survival in tumor-bearing mice.
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Breakthrough epigenetic study can improve the power to predict disease risk
The researchers hope their approach will have transformative effects in the field of epigenetic epidemiology.
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New method boosts the study of regulation of gene activity
The researchers report the development of a chemical-based sequencing method to quantify different epigenetic markers simultaneously.
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Tuberculosis induces premature cellular aging
It’s possible that premature cellular aging in TB is one reason why survivors have a three-fold increased risk of mortality.
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Sorting out cell type-specific molecular barcodes
Researchers at Baylor College of Medicine developed novel software that can distinguish methylation patterns within bulk WGBS data.
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A closer look at severe malnutrition
More than two million children die worldwide each year of severe malnutrition. Severe acute childhood malnutrition presents in two clinically distinct forms: edematous severe acute
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The making of a ‘couch potato mouse’
Some people love to exercise, but others hate it. Many researchers consider genetics to be the reason for a person’s inclination to exercise, or not
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Rearranging genomic structure rewires gene control in cancer
Widespread DNA damage is common in the cancer genome. Understanding the mechanisms that lead to it is of great interest to cancer physicians and scientists
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