Astrocytes come in specialized types that do different jobs in the brain
This study answers a long-standing question about astrocytes, star-shaped cells that are the most abundant support cells in the brain and spinal cord.
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Research
New treatment reduces heart scarring and abnormal heart rhythms, offering a possibility for future therapies
The researchers found that blocking a specific molecular interaction reversed established atrial fibrosis and reduced abnormal heart rhythms in a mouse model.
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Glioblastoma fights back and often defeats the brain’s defenses against tumor growth
The findings open the door to an entirely new way of thinking about treatment — not just targeting the tumor cells themselves, but also the signals between the tumor and the surrounding brain that let it thrive.
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Boosting the cell’s natural recycling center improves Alzheimer’s features in animal models
The findings suggest there is a possibility of translating these findings into therapy.
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Deep brain stimulation improves new neuron maturation for memory
DBS of a certain area of the brain can improve learning and memory in mouse model of Rett syndrome, offering new insights into the brain mechanisms involved in this disorder and potential future treatment targets.
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These cells are critical to the endometrium’s remarkable ability to regenerate
The researchers found that ALDH-positive cells in the healthy endometrium possess regenerative potential that is critical for endometrial development and function.
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New genetic findings help explain why autism affects males more often than females
The study reveals a role altered gene regulatory regions may play in autism.
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Building technologies to predict response to therapy in pediatric acute myeloid leukemia
The technologies identified tiny populations of cells in pre-treatment bone marrow that predicted relapse could occur months or years later
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Researchers link brain injury to brain tumors
The study supports continuing research into strategies that could reduce the risk of glioma growth in patients with a history of brain injury.
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Precision animal modeling reveals a spectrum of features in AXIN2-related disorders
This study is an example of the work conducted at the Center for Precision Medicine Models: connecting observations from patients to animal models and then translating those discoveries to improve diagnosis, counseling and care for families affected by rare genetic diseases.
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