Novel marker identifies cells that generate new neurons throughout life
Membrane-bound BASP-1 protein is a possible biomarker of neural stem cells that would allow the study of adult human neurogenesis.
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Research
In a cell-eat-cell world calcium ions regulate exposure of ‘eat-me’ signal in necrotic cells
New insights into the process of necrosis suggest that modulating the ‘eat-me’ signal may help reduce the toxic effects of cell death.
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Image of the Month: Brain of a mouse model of Huntington’s Disease
This confocal microscopy image shows a section of the brain of a mouse model of Huntington’s disease, with the astrocytes in green and cell nuclei in blue.
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Fasting lowers blood pressure by reshaping the gut microbiota
For the first time researchers show that intermittent fasting can reduce hypertension by reshaping the gut microbiota in an animal model.
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Focused on the Heart — Novel mouse model of myotonic dystrophy displays reversible cardiac disease features of the condition
This model of DM1 allows researchers to both focus on cardiac mechanisms of the disease and to expand therapeutics to target the heart.
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A new mechanism of cisplatin resistance in cancer, and how to reverse it
ACLT6A overexpression confers cancer cells resistance to cisplatin, and researchers found a way to reverse it.
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POT1 gene mutation predisposes to glioma and affects survival in a sex-specific manner
Researchers found gender differences in murine glioma lacking the gene Pot1, including survival, immune response, telomere length and DNA markers.
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Selecting the right deconvolution method just got easier
Extensive evaluation of existing deconvolution methods produced guidelines that scientists can use to determine the method that optimally fits their needs.
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Closer to human – mouse model more accurately reproduces fatty liver disease
A mouse model that closely replicates fatty liver disease can be used to better understand the condition and identify effective therapies.
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Prolonged infection and inflammation drain immune responses as we age
Sustained infection and inflammation wear down the immune system as we age reducing its ability to fight disease.
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