Researchers discover a vulnerability of acute myeloid leukemia
Exploiting this vulnerability resulted in rapid tumor regression in animal models of AML.
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epigenetics
Breakthrough epigenetic study can improve the power to predict disease risk
The researchers hope their approach will have transformative effects in the field of epigenetic epidemiology.
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Scientists propose that obesity is a neurodevelopmental disorder
The findings provide new evidence that developmental changes are likely involved in both early environmental and genetic influences on obesity risk.
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Unanticipated findings cast new light on the genetic regulation of different brain tumors
The findings highlight the importance of considering the mechanisms of gene regulation involved in different tumors when planning therapies.
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New method boosts the study of regulation of gene activity
The researchers report the development of a chemical-based sequencing method to quantify different epigenetic markers simultaneously.
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Tuberculosis induces premature cellular aging
It’s possible that premature cellular aging in TB is one reason why survivors have a three-fold increased risk of mortality.
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Machine learning meets biology to assess risk of schizophrenia in a blood sample
A novel machine learning approach can identify schizophrenia patients with 80% accuracy.
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Sorting out cell type-specific molecular barcodes
Researchers at Baylor College of Medicine developed novel software that can distinguish methylation patterns within bulk WGBS data.
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A closer look at severe malnutrition
More than two million children die worldwide each year of severe malnutrition. Severe acute childhood malnutrition presents in two clinically distinct forms: edematous severe acute
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The making of a ‘couch potato mouse’
Some people love to exercise, but others hate it. Many researchers consider genetics to be the reason for a person’s inclination to exercise, or not
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