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epigenetics

From The Labs 

Breakthrough epigenetic study can improve the power to predict disease risk

January 31, 2023January 31, 2023CoRSIVs, disease risk, DNA methylation, epigenetics, epigenome-wide association study, EWAS, Research

The researchers hope their approach will have transformative effects in the field of epigenetic epidemiology.

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From The Labs 

Scientists propose that obesity is a neurodevelopmental disorder

September 29, 2022September 29, 2022arcuate nucleus of the hypothalamus, epigenetics, food intake, mouse neurodevelopment, Obesity, Research

The findings provide new evidence that developmental changes are likely involved in both early environmental and genetic influences on obesity risk.

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From The Labs 

Unanticipated findings cast new light on the genetic regulation of different brain tumors

July 21, 2022July 21, 2022brain tumor, ependymoma, epigenetics, EPN, gene regulation, HGG, high-grade glioma, Research, SOX9, tumor behavior

The findings highlight the importance of considering the mechanisms of gene regulation involved in different tumors when planning therapies.

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From The Labs 

New method boosts the study of regulation of gene activity

June 30, 2022June 30, 2022DNA methylation, epigenetics, method, NT-seq, Research

The researchers report the development of a chemical-based sequencing method to quantify different epigenetic markers simultaneously.

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From The Labs 

Tuberculosis induces premature cellular aging

March 24, 2022March 24, 2022cellular aging, DNA methylation, epigenetic clock, epigenetics, Research, TB, tuberculosis

It’s possible that premature cellular aging in TB is one reason why survivors have a three-fold increased risk of mortality.

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From The Labs 

Machine learning meets biology to assess risk of schizophrenia in a blood sample

August 17, 2021August 17, 2021CoRSIVs, early diagnosis, epigenetics, machine learning, Psychiatry, Research, schizophrenia

A novel machine learning approach can identify schizophrenia patients with 80% accuracy.

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From The Labs 

Sorting out cell type-specific molecular barcodes

July 14, 2020August 11, 2020CluBCpG, DNA methylation, epigenetics, PReLIM, Research, WGBS

Researchers at Baylor College of Medicine developed novel software that can distinguish methylation patterns within bulk WGBS data.

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From The Labs 

A closer look at severe malnutrition

February 11, 2020February 11, 2020DNA methylation, epigenetics, ESAM, malnutrition, NESAM, Research

More than two million children die worldwide each year of severe malnutrition. Severe acute childhood malnutrition presents in two clinically distinct forms: edematous severe acute

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From The Labs 

The making of a ‘couch potato mouse’

December 30, 2019December 30, 2019AgRP neurons, couch potato, DNA methylation, epigenetics, Exercise, hypothalamus, overnutrition, Research

Some people love to exercise, but others hate it. Many researchers consider genetics to be the reason for a person’s inclination to exercise, or not

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From The Labs 

Rearranging genomic structure rewires gene control in cancer

November 14, 2019November 14, 2019Cancer, cancer genetics, Cancer Genome Atlas, DNA methylation, epigenetics, genomic structural variation, immune infiltration, Research

Widespread DNA damage is common in the cancer genome. Understanding the mechanisms that lead to it is of great interest to cancer physicians and scientists

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From the Labs Image of the Month

From The Labs Image of the Month From the Labs: a transparent heart

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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