Unanticipated findings cast new light on the genetic regulation of different brain tumors
The findings highlight the importance of considering the mechanisms of gene regulation involved in different tumors when planning therapies.
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epigenetics
New method boosts the study of regulation of gene activity
The researchers report the development of a chemical-based sequencing method to quantify different epigenetic markers simultaneously.
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Tuberculosis induces premature cellular aging
It’s possible that premature cellular aging in TB is one reason why survivors have a three-fold increased risk of mortality.
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Machine learning meets biology to assess risk of schizophrenia in a blood sample
A novel machine learning approach can identify schizophrenia patients with 80% accuracy.
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Sorting out cell type-specific molecular barcodes
Researchers at Baylor College of Medicine developed novel software that can distinguish methylation patterns within bulk WGBS data.
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A closer look at severe malnutrition
More than two million children die worldwide each year of severe malnutrition. Severe acute childhood malnutrition presents in two clinically distinct forms: edematous severe acute
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The making of a ‘couch potato mouse’
Some people love to exercise, but others hate it. Many researchers consider genetics to be the reason for a person’s inclination to exercise, or not
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Rearranging genomic structure rewires gene control in cancer
Widespread DNA damage is common in the cancer genome. Understanding the mechanisms that lead to it is of great interest to cancer physicians and scientists
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Image of the Month: Islet of Langerhans
Cells of the Islets of Langerhans in the pancreas help regulate blood sugar. Disrupting their normal function can contribute to the development of diabetes. The
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This map facilitates the search for epigenetic causes of disease
More than 15 years after scientists first mapped the human genome, most diseases still cannot be predicted based on one’s genes. Thus, researchers also are
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