Sorting out cell type-specific molecular barcodes
In the last 10 years, scientists generated thousands of whole genome bisulfite sequencing (WGBS) data sets costing millions of dollars, yet were unable to appreciate
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epigenetics
A closer look at severe malnutrition
More than two million children die worldwide each year of severe malnutrition. Severe acute childhood malnutrition presents in two clinically distinct forms: edematous severe acute
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The making of a ‘couch potato mouse’
Some people love to exercise, but others hate it. Many researchers consider genetics to be the reason for a person’s inclination to exercise, or not
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Rearranging genomic structure rewires gene control in cancer
Widespread DNA damage is common in the cancer genome. Understanding the mechanisms that lead to it is of great interest to cancer physicians and scientists
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Image of the Month: Islet of Langerhans
Cells of the Islets of Langerhans in the pancreas help regulate blood sugar. Disrupting their normal function can contribute to the development of diabetes. The
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This map facilitates the search for epigenetic causes of disease
More than 15 years after scientists first mapped the human genome, most diseases still cannot be predicted based on one’s genes. Thus, researchers also are
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Identical twins share more than identical genes
For decades, researchers have studied genetically identical twins to estimate what proportion of disease risk is determined by one’s genes. This approach should be reevaluated,
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Autism spectrum disorder: if not vaccines, then what?
New information gained from major scientific papers over the last two years has shed light on the causes and progression of autism spectrum disorder. Estimates
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Chromosome remodeler SETD2 also remodels the cytoskeleton in kidney cancer cells
Kidney cancer begins when certain genes mutate and, as a result, alter how key molecules work. One of these key molecules is SETD2, which is
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Novel epigenetic signature for tumor suppressors in normal cells found
By Glenna Vickers An epigenetic feature that may help identify novel cancer driver genes has been identified by researchers in the Dan L. Duncan Cancer
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