No NELL2, no sperm motility. Novel protein is essential for male fertility
Newly produced spermatozoa within the testis are not fully functional until they mature in the epididymis, a duct that helps
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From The Labs
Metabolomics meets genomics to improve patient diagnosis
A patient and family walk into a doctor’s office. They hope that the latest laboratory tests will reveal what is
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Image of the Month: Locating molecular players in Batten disease
Mutations in either protein CLN6 or CLN8 result in two forms of Batten disease with remarkably similar clinical features. It
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The single cell and the cluster, what makes one better than the other at cancer metastasis?
Cancer metastasis is all about rogue cancer cells abandoning the original tumor and venturing through the blood in search for
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Understanding the cancer risk in children with birth defects
Understanding the cancer risk in children with birth defects has been a challenge. Although scientific studies suggest that birth defects
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Slow-growing rotavirus mutant reveals early steps of viral assembly
Rotavirus is responsible for more than 130,000 deaths annually in infants and children younger than five years. The virus causes
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Unique sugar-sensing neurons work together to prevent severe hypoglycemia in mice.
Keeping blood sugar in balance can be a challenge, especially for people with type 1 diabetes who rely on intensive
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Premature epigenomic aging acts like a ‘sleeper cell’ that is awaken by Western-style diet
The epigenome is sometimes referred to as the “software” or “operating system” of the genome. It comprises small chemical modifications
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A novel mechanism that triggers a cellular immune response
Viruses and other disease-causing microbes influence the type of immune response their hosts will develop against them. In some cases,
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New clues on how lipid emulsions prevent liver disease in preterm babies
Infants born prematurely may require parenteral or intravenous nutrition to provide the necessary nourishment, as their digestive system is immature
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