From The Labs Archives - Baylor College of Medicine Blog Network

A better understanding of how the brain regulates body temperature during motion sickness may provide unconventional targets for the treatment of obesity.

Shot of a doctor writing notes while examining a senior patient in a clinic

From The Labs

Preventing onset and development of heart failure with preserved ejection fraction

April 15, 2025 EDEM2, heart failure with preserved ejection fraction, HFpEF, lipid toxicity, metabolic stress, Research, XBP1

The findings point at a promising new therapeutic target for mitigating heart lipid toxicity and heart failure.

From The Labs

Paving the way to better diagnosis and treatment for Langerhans cell histiocytosis

April 10, 2025 BRAFV600E mutation, Langerhans cell histiocytosis, Myeloid Neoplasia, Research, risk stratification

The findings create possibilities for risk-stratification regimens that can be better tailored to individual patients.

From The Labs

Baylor College of Medicine wins 2025 STAT Madness!

April 8, 2025 astrocytes, champion, Memory, neurons, Research, STAT Madness

This is the second year in a row that Baylor has won the popular vote in STAT’s bracket-style research competition.

From The Labs

New CDKL genes linked to neurodevelopmental disorders

April 3, 2025 CDKL genes, dominant negative effect, fruit fly, Neurological disorders, Research, seizures

Working with fruit flies, the team uncovered a mechanism by which the defective variants may cause the neurological symptoms in affected individuals.

From The Labs

New study helps researchers engineer better gene therapies

April 1, 2025 AAV, gene therapy, improved treatments, Research, viral vectors

This study will make basic research on AAV vectors for gene delivery and preclinical gene therapy studies in mice more efficient and reproducible.

A model valentine-style heart sitting next to a stethoscope.

From The Labs

Gasdermin D emerges as a potential therapeutic target for atrial fibrillation

March 27, 2025 atria, atrial fibrillation, Dementia, gasdermin D, heart cells, heart failure, mitochondria, reactive oxygen species, Research, Stroke

This study reveals that gasdermin D plays a novel role in the development of atrial fibrillation through multifaceted mechanisms.

A pregnant person's torso seen from the side, their arms wrapped around their stomach. A lush green wooded area is seen behind them.

From The Labs

Postpartum female preference for cooler temperatures linked to brain changes

March 25, 2025 body temperature, ERαPOA neurons, female temperature preference, lactation, mouse brain, Postpartum, Pregnancy, Research

Changes in temperature preference in postpartum female mice were associated with significant alterations in the preoptic area of the brain.

From The Labs

Medical student-mentor teams in research: Anna Norman and mentor Dr. Nancy Moran share their experience with SOAR

March 20, 2025 basic research training, carotenoids, genetics of skin carotenoids, medical students, research mentor, SOAR

Meet Anna Norman and her mentor Dr. Nancy Moran as they have a conversation about how the SOAR program brought them together to conduct basic science research and how the experience is shaping their careers.

From The Labs

Restoring heart function in Myotonic Dystrophy Type 1

March 18, 2025 DM1, DM1 therapies, heart problems, Myotonic Dystrophy Type 1, Research

The findings are relevant to current therapeutic approaches for DM1 that are based on increasing MBNL protein.

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