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From The Labs

From The Labs 

Overactive brain circuit causes anorexia in animal model

May 12, 2022May 12, 2022anorexia, brain circuit, dopamine, DRD1, Research, serotonin

Restoring the normal activity of a particular overactive brain circuit improved anorexia in an animal model of the condition.

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From The Labs 

New insights into the fate of dying cells

May 10, 2022May 10, 2022autophagy, C. elegans, CED-1, dying cells, DYN-1, lysosomes, phagocytosis, Research

The Zhou lab reveals a new player in the elimination of dying cells and identifies a mechanism for the process.

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From The Labs 

Image of the Month: A closer look at tertiary lymphoid structures

May 6, 2022May 6, 2022cancer biology, lung squamous cell carcinoma, Multiplex immunofluorescence, Research, tertiary lymphoid structures

Multiplex immunofluorescence reveals the immune landscape of cancer-associated tertiary lymphoid structures.

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From The Labs 

Stickiness is key for NANOG to turn on human cell pluripotency

May 5, 2022May 5, 2022chromatin reorganization, fluorescence fluctuation microscopy, NANOG, pluripotent stem cells, prion-like proteins, reserch

Researchers provide new insights into how human NANOG reshapes the genomic landscape to activate a pluripotent state.

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From The Labs 

Combating triple-negative breast cancer on two fronts delivers promising results

April 28, 2022April 28, 2022combination therapy, CSF1R, macrophages, Research, triple-negative breast cancer

Researchers identified a combination therapy for triple-negative breast cancer that results in durable tumor regression in an animal model.

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From The Labs 

Researchers reveal genetic basis of severe forms of EBF3-associated neurodevelopmental disorders

April 26, 2022May 3, 2022Autism, EBF3, HADDS, neurodevelopmental disorders, Research, zinc finger domain

Patients with some gene variants affecting a zinc finger region of EBF3 suffer from a more severe form of the condition.

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From The Labs 

Baylor researcher awarded a Marie Curie Global Fellowship

April 21, 2022April 21, 2022angioedema, Cancer, Cardiovascular Disease, Curie Postdoctoral Fellowships, kallikrein-kinin system, mass spectrometric imaging, Research

Dr. Bjoern Burckhardt will use mass spectrometric imaging to identify potential new biomarkers and promising drug targets for human diseases.

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From The Labs 

Interferon drives cognitive impairment in Alzheimer’s disease model

April 19, 2022April 19, 2022Alzheimer's Disease, cognitive impairment, inflammation, Research, synapse loss, Type I Interferon

This study highlights the importance of brain inflammation and other complex events involved in the development of Alzheimer’s disease.

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Brain-with-DNA-featured
From The Labs 

The discovery of genes like PAX5 improves diagnostic testing for neurodevelopmental disorders, and more

April 14, 2022April 14, 2022genetic diagnosis, neurodevelopmental disorders, PAX5, Research, undiagnosed diseases

Discovering new genes that are linked to undiagnosed diseases has relevant scientific and clinical consequences as well as important personal implications for patients.

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From The Labs 

April is National Autism Awareness Month

April 12, 2022April 12, 2022fruit fly, microbiome, National Autism Awareness Month, PTEN, Research, single-cell connections, Vaccines

From the Labs presents a sample of Baylor’s basic research work contributing to a better understanding of autism and related disorders.

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From the Labs Image of the Month

From The Labs Image of the Month From the Labs: A closer look at tertiary lymphoid structures. Image courtesy of M. Zelazowski/ P. Castro/Baylor’s Human Tissue Acquisition & Pathology (HTAP) Core.

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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