Artificial intelligence reveals a never-before described 3D structure in rotavirus spike protein
The findings are an example of how viruses can evolve by incorporating structurally distinct modules with similar functionality.
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rotavirus
Image (video) of the Month: human intestinal organoid after infection with rotavirus
This video placed first in the 2021 FASEB BioArt contest: video category. Congratulations, JT Gebert and the Hyser lab!
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How a few rotavirus can cause severe gastrointestinal disease
Using intercellular calcium waves, rotavirus amplifies its ability to cause disease beyond the cells it directly infects.
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Slow-growing rotavirus mutant reveals early steps of viral assembly
Rotavirus is responsible for more than 130,000 deaths annually in infants and children younger than five years. The virus causes severe, dehydrating diarrhea as it
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Mystery solved, rotavirus VP3 is a unique capping machine
After eluding researchers for more than 30 years, the VP3 protein of rotavirus has finally revealed its unique structure and function to a team led
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‘Give me the calcium!’ Tulane virus takes over cellular calcium signaling to replicate
Some gastrointestinal viruses need calcium. They need calcium ions to carry out several essential aspects of viral life, such as entry into host cells, genome
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Video of the Month: A calcium storm
From the Labs opens July 2019 with a Video of the Month, showing the calcium ‘storm’ rotavirus triggers in infected cells. Calcium signaling in rotavirus
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‘Can you hear me, now?’ A new strategy ‘raises the volume’ of hard-to-detect gut-body communication
Throughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells and, although they comprise only a small population of the total cells, they
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Image of the Month: Assembling a rotavirus factory
Making new viruses requires assembling intracellular replication factories via a complex, little known process that involves both viral and cellular components. New insights into this
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Baylor College of Medicine faculty members elected fellows of the National Academy of Inventors
Drs. Mary K. Estes, Bert O’Malley and Huda Zoghbi of Baylor College of Medicine were three of the 148 renowned academic inventors named fellows of
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