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PI3K pathway

From The Labs

De-escalating breast cancer therapy; can some patients be spared chemotherapy?

June 25, 2019 Breast Cancer, Chemotherapy, Clinical Trials, HER2 gene, lapatinib, PI3K pathway, Research, trastuzumab

About one of every five breast cancers presents with high levels of HER2 proteins. Known as HER2-positive breast cancer, these tumors typically show an aggressive

From The Labs

What activates the PI3K pathway, the most commonly mutated pathway in cancer that can be targeted by drugs?

July 31, 2017 cancer mutations, Cancer pathways, IDH1 gene, personalized medicine, PI3K pathway, The Cancer Genome Atlas, VHL gene

The PI3K pathway has a number of diverse functions, including altering the cell’s metabolism and driving cell growth and proliferation. The PI3K pathway also is

From the Labs: Human retinal organoid.