Study of spliceosome-targeting cancer therapies reveals an overlooked role of mis-spliced RNAs themselves
Endogenous mis-spliced RNA in tumor cells mimics an RNA virus, leading tumor cells to self-destruct as if fighting an infection.
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Immunotherapy
CAR NKT cells, a promising step forward in the treatment of solid tumors
An ongoing clinical trial shows that human CAR NKT cells are safe and, in 1 of 3 patients, induced regression of metastatic lesions.
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New insights into the mediators of patient recovery after CAR T cell immunotherapy
Clinical trial of novel personalized CAR T cell immunotherapy provides clues into what mediated exceptional patient recovery.
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Immunotherapy improves quality of life for mesothelioma patient
When Samir Tanios was diagnosed with malignant pleural mesothelioma in September 2018, he was in poor condition. He couldn’t take a deep breath or walk
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Body of Work podcast: Harnessing the body’s immune system to fight cancer
By 2030, the number of new cancer cases per year is expected to increase by 23.6 million worldwide. While radiation and chemotherapy continue to be
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Immunotherapy for pancreatic cancer shows promise
Pancreatic cancer is one of the most challenging types of cancer to treat, but new therapy using the body’s own immune system is providing new
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How immunotherapy is improving outlook for melanoma patients
Melanoma is the deadliest form of skin cancer in the world. While traditional therapies include chemotherapy, radiation, and surgery, immunotherapy has emerged as an effective
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From the labs to bedside: First-in-human trial shows promise in treating neuroblastoma
Neuroblastoma is the most common extracranial solid cancer in children, and patients with high-risk disease are challenging to treat. In April, during the annual meeting of
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Special delivery of IL-7 signaling makes all the difference for CAR T cells fighting solid tumors
Since he was in college, Thomas Shum wanted to pursue a career in cancer research. As he advanced in his studies, he was able to
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Immunotherapy treatment gives lung cancer patient second chance
A few years ago, Katherine Dill was leading a full life with her two children in Texas when she noticed something different about her face.
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