Ana Rodríguez, Author at Baylor College of Medicine Blog Network

Understanding the cell waste disposal problems in Lou Gehrig’s disease

March 12, 2019 ALS, Alzheimer's Disease, autophagy, Drosophila, fruit fly, Lou Gehrig's disease, lysosomes, proteasome, Research, ubiquilin

Building up cellular waste is bad news for cells, and particularly for neurons. Such excessive build up can lead to neurological conditions, as is the

From The Labs

SHANK3: the good, the bad and the hopeful

March 7, 2019 Autism, ERK2, kinases, missense mutation, Phelan-McDermid syndrome., Research, S685I, SHANK3

Some neuropsychiatric conditions may boil down to how well brain cells communicate with each other. This can be affected by a number of factors, including

From The Labs

Image of the Month: Trachea and Vasculature of the Mouse Lung

March 5, 2019 Baylor core labs, cardiac development, Cardiovascular Disease, OIVMC, Optical Imaging and Vital Microscopy Core, Research, septum, vascular development

In his lab at Baylor College of Medicine, Dr. Joshua D. Wythe and his colleagues conduct cardiovascular research covering the following areas: Vascular Development, trying

From The Labs

Tuberous sclerosis: it’s not all about mTORC1

February 28, 2019 glycogen, lysosomes, mTORC1, Research, TSC, tuberous sclerosis

mTORC1, a protein complex that regulates cell metabolism, has long been considered the major driving force behind tuberous sclerosis. New experimental evidence, however, is challenging

From The Labs

A worm’s lessons for living a longer, healthier life

February 26, 2019 Aging, C. elegans, fat metabolism, Longevity, lysosomes, metabolic signaling, mitochondria, oxidative tolerance, Research, sugar metabolism

Caenorhabditis elegans is a seemingly unimpressive worm. It is as long as a penny is thick, it lives in the soil feeding on microbes it

From The Labs

CD44 variants prompt different cancer cell behaviors

February 21, 2019 alternative splicing, Breast Cancer, cancer heterogeneity, cancer plasticity, CD44, Metastasis, Research, resistance to treatment

Imagine fighting enemies that differ in their susceptibility to the weapon you are using against them. Some will perish, but others will survive the attack

From The Labs

This brain circuit allows the feeding and memory centers to talk to each other

February 19, 2019 appetite, Brain, chromosome 17, hippocampus, hypothalamus, intellectual disability, Memory, NCOR1/2, neurodevelopmental defects, Research

It was not what the researchers were expecting to find when they set out to investigate how the protein complex NCOR1/2 regulates memory. “We knew

From The Labs

Research that celebrates Heart Month

February 14, 2019 antibioics, atrial fibrilation, ciprofloxacin, Heart Health, Heart month, heart regeneration, Hippo, inflammasome, p63, Research

From the Labs celebrates Heart Month and Valentine’s Day with a selection of posts about the heart. We feature research findings that have resulted in

From The Labs

Genome sequencing reveals baboon evolution, and more

February 12, 2019 baboon evolution, Genome Sequencing, human evolution, Research

Can baboon genome sequencing give a hint at human evolution? “Baboons have long attracted scientific attention because they evolved within the same sub-Saharan African habitat

From The Labs

Uncovering a pathway that protects the uterus from cancer

February 7, 2019 ALK5, carcinoma of endometrium, estrogen, female fertility, Research, Smad2, SMAD3, TGF-beta, uterine cancer

The TGF-beta signaling pathway regulates the development of many types of cancer, but it was not clear whether it also played a role in uterine