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spliceosome

From The Labs

When tau tangles, RNA errors can happen in Alzheimer’s disease

October 17, 2019October 17, 2019 Ana Rodríguez 0 Comments Alzheimer's Disease, Research, RNA splicing errors, spliceosome, tau protein, tau tangles

The tau protein is a key player in Alzheimer’s disease. It tangles and accumulates inside brain cells and this, in combination with increasing cell death,

From The Labs

Mutations in CWC27 result in spectrum of conditions

April 13, 2017 Ana Rodríguez 0 Comments blindness, craniofacial and skeletal problems, CWC27, Genetics, Retinitis pigmentosa, spliceosome, whole exome sequencing

Mingchu Xu searches for genes linked to retinitis pigmentosa, a condition of the retina characterized by progressive development of night blindness and tunnel vision, sometimes from

From the Labs features an image pinpointing the location of Man1b1 inside the cell, which sharpened the view of cellular regulation of protein homeostasis. Image courtesy of the Sifers lab/Molecular Biology of the Cell, 2011.