New research moves novel gene therapy for heart failure closer to the clinic
Knocking down the Hippo signaling pathway in pig cardiomyocytes after a heart attack, resulted in heart tissue renewal and improved function.
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cardiomyocytes
What the Hippo pathway in cardiac fibroblasts reveals about heart function
Heart failure remains the leading cause of mortality in the U.S. During a heart attack, blood stops flowing into the heart. Without oxygen, part of
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Preventing sudden cardiac death with genome editing
Each year, at least 3 million people worldwide die of sudden cardiac death. In the U.S., this number reaches up to 450,000 people. Although sudden
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Eliminating p63 gene could convert scar tissue into heart muscle
After a heart attack, the parts of the heart muscle that die do not regenerate into new heart tissue; instead, they are replaced by scar
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How Gata4 helps mend a broken heart
During a heart attack, blood stops flowing into the heart; starved for oxygen, part of the heart muscle dies. The heart muscle does not regenerate;
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