Study reveals heterogeneity of bone metastases across different and same cancer types
The results of this study suggest a need to investigate different treatment strategies for different immune ecosystem patterns in bone metastases.
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tumor microenvironment
Image of the Month: A closer look at metastatic medulloblastoma
The image captures metastatic medulloblastoma tumor cells (green) intertwined with blood vessels (magenta) in the leptomeninges of a mouse model of the human condition.
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Partners in crime: Metastatic medulloblastoma recruits local fibroblasts to support its spread and growth
This novel discovery shows how tumor and non-tumor cells work together to create an environment that backs up cancer growth.
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Fatty acids promote immune suppression and therapy resistance in triple negative breast cancer
The researchers show that disrupting lipid formulation reverses treatment resistance and the immunosuppressive microenvironment.
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Eliminating gene SRC-3 in immune cells triggers effective long-lasting anti-cancer response
The findings in animal models warrant continuing investigations to develop a novel, more effective and longer-lasting cancer therapy.
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Changes in gene p16 create a permissive microenvironment for colon cancer growth
The researchers also developed a strategy that reduced tumor growth and improved survival in tumor-bearing mice.
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Taking a closer look into the tumor microenvironment with nano-radiomics
Nano-radiomics analysis of imaging data assesses changes in the tumor microenvironment that cannot be detected with conventional imaging methods.
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What extensive protein analysis revealed about cancer
Cancer is currently understood not as a single disease, but as a collection of diseases that can develop through alterations in different molecular pathways. This
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What to expect within the tumor microenvironment
Breast cancer is very heterogeneous. For many years researchers have recognized different subtypes of breast cancer, for instance, estrogen receptor positive (ER+), ER- and triple
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