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Aging

From The Labs 

GlyNAC supplementation extends life span in mice

March 8, 2022March 15, 2022Aging, glutathione, GlyNAC, hallmarks of aging, mitochondrial deficiency, mouse model, oxidative stress, Research

GlyNAC – a combination of precursors of the natural antioxidant glutathione – can increase lifespan and improve multiple key age-associated defects in mice.

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From The Labs 

Elevated cryptic transcription emerges as a common theme in aging mammalian cells

August 24, 2021August 24, 2021Aging, cryptic transcription, DNA coe, Research, stem cells

Evidence suggests that reducing the amount of this aberrant transcription in aging organisms might help prolong lifespan.

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From The Labs 

Prolonged infection and inflammation drain immune responses as we age

April 8, 2021April 8, 2021Aging, clonal hematopoiesis, Dnmt3a, hematopoietic stem cells, IFNgamma, inflammation, prolonged infection, Research

Sustained infection and inflammation wear down the immune system as we age reducing its ability to fight disease.

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From The Labs 

Image of the Month: The laboratory worm, C. elegans

March 2, 2021March 2, 2021Aging, bacteria, C. elegans, Image of the month, lipid signaling, mitochondria, Research

What is transparent, as long as a credit card is thick and helps solve science mysteries? The laboratory worm, C. elegans.

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From The Labs 

Light-activated genes illuminate the role of gut microbes in longevity

January 28, 2021January 28, 2021Aging, C. elegans, colanic acid, Longevity, microbiome, optogenetics, Research

Optogenetics, a method that uses light to regulate gene expression, can control gut bacterial metabolism to promote longevity.

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From The Labs 

Glutathione precursor GlyNAC reverses premature aging in people with HIV

October 15, 2020October 15, 2020Aging, glutathione, GlyNAC, HIV, Research

Twenty years of research support the role of antioxidant glutathione in reversing premature aging in people with HIV.

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From The Labs 

Early postnatal overnutrition sets the body on a fast track to aging

September 19, 2019September 26, 2019Aging, Diabetes, DNA methylation, infancy, Obesity, overnutrition, Research

Overnutrition during early infancy can have adverse health consequences later in life. Although researchers have known this for quite some time, the explanations have been

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From The Labs 

Extending the body’s expiration date may involve the ends of the chromosomes

April 4, 2019April 4, 2019Aging, ends of chromosomes, liver fibrosis, NAD+ precursor, NMN, Research, sirtuin, telomeres

Scientists may have found a strategy to achieve the science-fictional greeting “Live long and prosper.” In his lab at Baylor College of Medicine, Dr. Ergun

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From The Labs 

A worm’s lessons for living a longer, healthier life

February 26, 2019February 26, 2019Aging, C. elegans, fat metabolism, Longevity, lysosomes, metabolic signaling, mitochondria, oxidative tolerance, Research, sugar metabolism

Caenorhabditis elegans is a seemingly unimpressive worm. It is as long as a penny is thick, it lives in the soil feeding on microbes it

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From The Labs 

Alternative splicing is crucial to muscle mass maintenance

July 10, 2018February 3, 2020Aging, alternative splicing, chronic disease, muscle mass maintenance, Rbfox1, Rbfox2, Research

Despite the importance that changes in muscle mass have in aging, overall body metabolism and in chronic disease, we still don’t fully understand the mechanisms

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From the Labs Image of the Month

From The Labs Image of the Month From the Labs: A closer look at tertiary lymphoid structures. Image courtesy of M. Zelazowski/ P. Castro/Baylor’s Human Tissue Acquisition & Pathology (HTAP) Core.

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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