Metastasis Archives - Baylor College of Medicine Blog Network

Image of the Month: A closer look at metastatic medulloblastoma

May 6, 2025 blood vessels, brain cancer, fibroblasts, medulloblastoma, meninges, Metastasis, Research, tumor microenvironment

The image captures metastatic medulloblastoma tumor cells (green) intertwined with blood vessels (magenta) in the leptomeninges of a mouse model of the human condition.

From The Labs

Partners in crime: Metastatic medulloblastoma recruits local fibroblasts to support its spread and growth

May 1, 2025 BMP, brain cancer, fibroblast, leptomeninges, medulloblastoma, Metastasis, PDGF, Research, tumor microenvironment

This novel discovery shows how tumor and non-tumor cells work together to create an environment that backs up cancer growth.

From The Labs

State of the Lester and Sue Smith Breast Center and breast cancer research

January 19, 2023 animal cancer models, Breast Center, cancer immunology, drug development, drug repurposing, Metastasis, patient care, Research

Interim director Dr. Xiang “Shawn” Zhang sat down with From the Labs to provide an update on this multidisciplinary center dedicated to breast cancer research and patient care.

From The Labs

Carbon ultrafine particles accelerate lung cancer progression

November 29, 2022 carbon ultrafine particles, cigarette smoke, lung cancer, Metastasis, Research, smoking

Researchers at Baylor College of Medicine discover how airborne ultrafine particles in smoke can change a host’s defense against lung cancer.

From The Labs

A potentially more effective treatment for HER2 mutant metastatic breast cancer

June 23, 2022 Breast Cancer, cancer treatment, HER2 mutations, lobular breast cancer, Metastasis, neratinib, poziotinib, Research

A phase II clinical trial is on its way to assess the value of poziotinib in the treatment of this devastating condition.

From The Labs

The bone microenvironment ‘empowers’ cancer cells to become metastatic

May 18, 2021 bone microenvironment, Breast Cancer, EZH2, Metastasis, Prostate Cancer, Research

The bone microenvironment prompts changes in breast cancer cells that help them escape treatment and become more invasive.

From The Labs

The single cell and the cluster, what makes one better than the other at cancer metastasis?

June 30, 2020 Breast Cancer, cluster cancer cells, Metastasis, NK cells, Research

Cancer metastasis is all about rogue cancer cells abandoning the original tumor and venturing through the blood in search for new breeding grounds. Sometimes, single

From The Labs

CD44 variants prompt different cancer cell behaviors

February 21, 2019 alternative splicing, Breast Cancer, cancer heterogeneity, cancer plasticity, CD44, Metastasis, Research, resistance to treatment

Imagine fighting enemies that differ in their susceptibility to the weapon you are using against them. Some will perish, but others will survive the attack

From The Labs

An integrated approach to finding new treatments for breast cancer

December 11, 2018 DPYSL3, Metastasis, proteogenomics, Research, triple-negative breast cancer, vimentin

Unraveling the complexity of cancer biology can lead to the identification new molecules involved in breast cancer and prompt new avenues for drug development. And

From The Labs

Estrogen receptor can affect resistance to endocrine therapy and metastasis in breast cancer

October 25, 2018 Breast Cancer, ESR1, estrogen receptor-positive, Metastasis, Research, resistance to endocrine therapy

Resistance to therapy is common in estrogen receptor positive (ER+) breast cancer, the most common type of breast cancer, and eventual development of metastatic disease

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