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Metastasis

From The Labs 

State of the Lester and Sue Smith Breast Center and breast cancer research

January 19, 2023January 19, 2023animal cancer models, Breast Center, cancer immunology, drug development, drug repurposing, Metastasis, patient care, Research

Interim director Dr. Xiang “Shawn” Zhang sat down with From the Labs to provide an update on this multidisciplinary center dedicated to breast cancer research and patient care.

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From The Labs 

Carbon ultrafine particles accelerate lung cancer progression

November 29, 2022November 29, 2022carbon ultrafine particles, cigarette smoke, lung cancer, Metastasis, Research, smoking

Researchers at Baylor College of Medicine discover how airborne ultrafine particles in smoke can change a host’s defense against lung cancer.

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From The Labs 

A potentially more effective treatment for HER2 mutant metastatic breast cancer

June 23, 2022June 23, 2022Breast Cancer, cancer treatment, HER2 mutations, lobular breast cancer, Metastasis, neratinib, poziotinib, Research

A phase II clinical trial is on its way to assess the value of poziotinib in the treatment of this devastating condition.

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From The Labs 

The bone microenvironment ‘empowers’ cancer cells to become metastatic

May 18, 2021May 18, 2021bone microenvironment, Breast Cancer, EZH2, Metastasis, Prostate Cancer, Research

The bone microenvironment prompts changes in breast cancer cells that help them escape treatment and become more invasive.

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From The Labs 

The single cell and the cluster, what makes one better than the other at cancer metastasis?

June 30, 2020October 14, 2021Breast Cancer, cluster cancer cells, Metastasis, NK cells, Research

Cancer metastasis is all about rogue cancer cells abandoning the original tumor and venturing through the blood in search for new breeding grounds. Sometimes, single

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From The Labs 

CD44 variants prompt different cancer cell behaviors

February 21, 2019February 21, 2019alternative splicing, Breast Cancer, cancer heterogeneity, cancer plasticity, CD44, Metastasis, Research, resistance to treatment

Imagine fighting enemies that differ in their susceptibility to the weapon you are using against them. Some will perish, but others will survive the attack

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From The Labs 

An integrated approach to finding new treatments for breast cancer

December 11, 2018December 11, 2018DPYSL3, Metastasis, proteogenomics, Research, triple-negative breast cancer, vimentin

Unraveling the complexity of cancer biology can lead to the identification new molecules involved in breast cancer and prompt new avenues for drug development. And

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From The Labs 

Estrogen receptor can affect resistance to endocrine therapy and metastasis in breast cancer

October 25, 2018October 25, 2018Breast Cancer, ESR1, estrogen receptor-positive, Metastasis, Research, resistance to endocrine therapy

Resistance to therapy is common in estrogen receptor positive (ER+) breast cancer, the most common type of breast cancer, and eventual development of metastatic disease

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From The Labs 

This is what the Warburg pathway can do for breast cancer growth

May 17, 2018May 18, 2018Breast Cancer, glucose metabolism, Metastasis, PFKFB4, Research, SRC-3, Warburg pathway

To generate energy from glucose, cells can use one of two pathways. One of them takes place in the mitochondria, energy-producing structures inside cells, and

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From The Labs 

Device that induces a mild localized ‘fever’ could treat vascular involvement in cancer

November 2, 2017CorleyWare device, hyperthermia, Innovation in cancer treatment, innovative technology, Metastasis, pancreatic cancer, positive margin

The prognosis of a cancer patient relies significantly on the ability of the surgeon to remove all the tumor, including a cancer-free boundary, leaving what

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From the Labs Image of the Month

From The Labs Image of the Month From the Labs: Adult-born neurons made the cover

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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