Metastasis Archives - Baylor College of Medicine Blog Network

The bone microenvironment prompts changes in breast cancer cells that help them escape treatment and become more invasive.

From The Labs

The single cell and the cluster, what makes one better than the other at cancer metastasis?

June 30, 2020October 14, 2021Breast Cancer, cluster cancer cells, Metastasis, NK cells, Research

Cancer metastasis is all about rogue cancer cells abandoning the original tumor and venturing through the blood in search for new breeding grounds. Sometimes, single

From The Labs

CD44 variants prompt different cancer cell behaviors

February 21, 2019February 21, 2019alternative splicing, Breast Cancer, cancer heterogeneity, cancer plasticity, CD44, Metastasis, Research, resistance to treatment

Imagine fighting enemies that differ in their susceptibility to the weapon you are using against them. Some will perish, but others will survive the attack

From The Labs

An integrated approach to finding new treatments for breast cancer

December 11, 2018December 11, 2018DPYSL3, Metastasis, proteogenomics, Research, triple-negative breast cancer, vimentin

Unraveling the complexity of cancer biology can lead to the identification new molecules involved in breast cancer and prompt new avenues for drug development. And

From The Labs

Estrogen receptor can affect resistance to endocrine therapy and metastasis in breast cancer

October 25, 2018October 25, 2018Breast Cancer, ESR1, estrogen receptor-positive, Metastasis, Research, resistance to endocrine therapy

Resistance to therapy is common in estrogen receptor positive (ER+) breast cancer, the most common type of breast cancer, and eventual development of metastatic disease

From The Labs

This is what the Warburg pathway can do for breast cancer growth

May 17, 2018May 18, 2018Breast Cancer, glucose metabolism, Metastasis, PFKFB4, Research, SRC-3, Warburg pathway

To generate energy from glucose, cells can use one of two pathways. One of them takes place in the mitochondria, energy-producing structures inside cells, and

From The Labs

Device that induces a mild localized ‘fever’ could treat vascular involvement in cancer

November 2, 2017CorleyWare device, hyperthermia, Innovation in cancer treatment, innovative technology, Metastasis, pancreatic cancer, positive margin

The prognosis of a cancer patient relies significantly on the ability of the surgeon to remove all the tumor, including a cancer-free boundary, leaving what

From The Labs

Out of the body and into bone-in culture: new technique tests drugs for metastatic cancer

June 29, 2017Breast Cancer, Metastasis

For many cancer patients, the problem is metastasis – the dissemination of tumor cells to other organs – after the primary tumor has been eliminated.

From The Labs

How breast cancer can become resistant to hormone therapy

January 9, 2017Breast cancer resistance, Brest cancer resistance, estrogen receptor-positive, FOXA1, IL-8, Metastasis, tamoxifen

Despite the overall success of hormone therapy, breast cancer tumors in patients with metastatic disease often fail to respond. One new mechanism that can explain

From The Labs

Mouse model shows that Notch activation can drive metastatic prostate cancer

August 23, 2016May 4, 2018Metastasis, metastatic prostate cancer, mouse model, Notch signaling pathway, Prostate Cancer, Pten gene, Research

Nearly 200 thousand men are diagnosed with prostate cancer every year. Most of the deaths associated with prostate cancer occur in advanced stages of the