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estrogen receptor-positive

From The Labs 

Losing neurofibromin is good news for breast cancer

March 24, 2020March 25, 2020Breast Cancer, ER-corepresor, estrogen receptor-positive, fulvestrant, MEK inhibitor, neurofibromin, Ras, Research

It is well known that neurofibromin (NF1), a tumor suppressor produced by the NF1 gene, keeps cancer growth in check by repressing the activity of

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From The Labs 

Estrogen receptor can affect resistance to endocrine therapy and metastasis in breast cancer

October 25, 2018October 25, 2018Breast Cancer, ESR1, estrogen receptor-positive, Metastasis, Research, resistance to endocrine therapy

Resistance to therapy is common in estrogen receptor positive (ER+) breast cancer, the most common type of breast cancer, and eventual development of metastatic disease

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From The Labs 

How breast cancer can become resistant to hormone therapy

January 9, 2017Breast cancer resistance, Brest cancer resistance, estrogen receptor-positive, FOXA1, IL-8, Metastasis, tamoxifen

Despite the overall success of hormone therapy, breast cancer tumors in patients with metastatic disease often fail to respond. One new mechanism that can explain

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From the Labs Image of the Month

From The Labs Image of the Month From the Labs: A closer look at tertiary lymphoid structures. Image courtesy of M. Zelazowski/ P. Castro/Baylor’s Human Tissue Acquisition & Pathology (HTAP) Core.

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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