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From The Labs

Losing neurofibromin is good news for breast cancer

March 24, 2020 Breast Cancer,  ER-corepresor,  estrogen receptor-positive,  fulvestrant,  MEK inhibitor,  neurofibromin,  Ras,  Research

It is well known that neurofibromin (NF1), a tumor suppressor produced by the NF1 gene, keeps cancer growth in check by repressing the activity of

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From The Labs

Estrogen receptor can affect resistance to endocrine therapy and metastasis in breast cancer

October 25, 2018 Breast Cancer,  ESR1,  estrogen receptor-positive,  Metastasis,  Research,  resistance to endocrine therapy

Resistance to therapy is common in estrogen receptor positive (ER+) breast cancer, the most common type of breast cancer, and eventual development of metastatic disease

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From The Labs

How breast cancer can become resistant to hormone therapy

January 9, 2017 Breast cancer resistance,  Brest cancer resistance,  estrogen receptor-positive,  FOXA1,  IL-8,  Metastasis,  tamoxifen

Despite the overall success of hormone therapy, breast cancer tumors in patients with metastatic disease often fail to respond. One new mechanism that can explain

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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