Fatty acids promote immune suppression and therapy resistance in triple negative breast cancer
The researchers show that disrupting lipid formulation reverses treatment resistance and the immunosuppressive microenvironment.
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DAPK3 emerges as a new regulator of migration of triple-negative breast cancer cells
The researchers’ next steps include studying how DAPK3 promotes TNBC migration and assess its potential value as a therapeutic target.
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Anticipating treatment response in triple negative breast cancer
A new blood biomarker discovered in triple negative breast cancer patients could potentially indicate response to treatment.
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eIF4A emerges as a potential Achilles’ heel for triple-negative breast cancer
Targeting eIF4A to interfere with the synthesis of proteins the cancer needs to grow is producing promising results.
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A potential strategy to control MAPK4-dependent cancer growth
This study has advanced our understanding of the molecular mechanisms underlying the tumor-promoting activity of MAPK4.
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Serendipity reveals an opportunity to improve the success of chemotherapy in triple negative breast cancer
Researchers identified a tumor protein signature that predicts chemotherapy sensitivity and favorable clinical outcomes.
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Research reveals markers of chemotherapy resistance and outcome in triple negative breast cancer
The findings help predict tumor response so that only effective treatments are given.
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Combating triple-negative breast cancer on two fronts delivers promising results
Researchers identified a combination therapy for triple-negative breast cancer that results in durable tumor regression in an animal model.
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Targeting MAPK4 may offer a new therapeutic opportunity for TNBC
MAPK4 seems to be involved in promoting triple-negative breast cancer growth and its resistance to certain therapies.
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Study of spliceosome-targeting cancer therapies reveals an overlooked role of mis-spliced RNAs themselves
Endogenous mis-spliced RNA in tumor cells mimics an RNA virus, leading tumor cells to self-destruct as if fighting an infection.
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