triple-negative breast cancer Archives - Baylor College of Medicine Blog Network

A new blood biomarker discovered in triple negative breast cancer patients could potentially indicate response to treatment.

From The Labs

eIF4A emerges as a potential Achilles’ heel for triple-negative breast cancer

October 31, 2023 cancer vulnerability, eIF4A, Research, triple-negative breast cancer, Zotatifin

Targeting eIF4A to interfere with the synthesis of proteins the cancer needs to grow is producing promising results.

Two slides showing breast cancer cells as blue or green dots on a blue background.

From The Labs

A potential strategy to control MAPK4-dependent cancer growth

August 8, 2023 AKT, cancer growth, lung cancer, MAPK4, PDK1, Prostate Cancer, Research, triple-negative breast cancer

This study has advanced our understanding of the molecular mechanisms underlying the tumor-promoting activity of MAPK4.

From The Labs

Serendipity reveals an opportunity to improve the success of chemotherapy in triple negative breast cancer

July 27, 2023 kinase inhibitor, KIPA, purine-binding protein, Research, TNBC, triple-negative breast cancer

Researchers identified a tumor protein signature that predicts chemotherapy sensitivity and favorable clinical outcomes.

From The Labs

Research reveals markers of chemotherapy resistance and outcome in triple negative breast cancer

September 6, 2022 chemotherapy resistance, microscaled proteogenomics, Research, triple-negative breast cancer

The findings help predict tumor response so that only effective treatments are given.

From The Labs

Combating triple-negative breast cancer on two fronts delivers promising results

April 28, 2022 combination therapy, CSF1R, macrophages, Research, triple-negative breast cancer

Researchers identified a combination therapy for triple-negative breast cancer that results in durable tumor regression in an animal model.

From The Labs

Targeting MAPK4 may offer a new therapeutic opportunity for TNBC

January 27, 2022 AKT, cancer therapy, MAPK4, PI3K, PI3K inhibitor, Research, triple-negative breast cancer

MAPK4 seems to be involved in promoting triple-negative breast cancer growth and its resistance to certain therapies.

From The Labs

Study of spliceosome-targeting cancer therapies reveals an overlooked role of mis-spliced RNAs themselves

January 19, 2021 apoptosis, cancer treatment, Immunotherapy, Research, RNA splicing, Spliceosome-targeting therapies, triple-negative breast cancer

Endogenous mis-spliced RNA in tumor cells mimics an RNA virus, leading tumor cells to self-destruct as if fighting an infection.

From The Labs

An integrated approach to finding new treatments for breast cancer

December 11, 2018 DPYSL3, Metastasis, proteogenomics, Research, triple-negative breast cancer, vimentin

Unraveling the complexity of cancer biology can lead to the identification new molecules involved in breast cancer and prompt new avenues for drug development. And

From The Labs

A potential new purpose for an old drug

November 20, 2018 autophagy, flunarizine, Ras, Research, triple-negative breast cancer

When it comes to finding new drugs to treat breast cancer, some scientists are taking an approach that could expedite the discovery of new treatments.

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