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Prostate Cancer

A microscopic view of prostate cancer. It appears as a field of hazy pink and white with splotches of purple indicating cancer cells.
From The Labs 

A novel strategy to suppress prostate cancer growth

October 26, 2022November 3, 2022androgen receptor, castration therapy, COP1, Gata2, Prostate Cancer, Research, treatment resistance

The researchers took a close look into what drives the growth of advanced tumors that have become resistant to standard castration therapy.

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From The Labs 

The bone microenvironment ‘empowers’ cancer cells to become metastatic

May 18, 2021May 18, 2021bone microenvironment, Breast Cancer, EZH2, Metastasis, Prostate Cancer, Research

The bone microenvironment prompts changes in breast cancer cells that help them escape treatment and become more invasive.

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From The Labs 

Targeting MAPK4 emerges as a promising therapy for prostate cancer

February 23, 2021February 23, 2021Akt pathway, androgen receptor, cancer therapy, castration-resistant prostate cancer, MAPK4, Prostate Cancer, Research

Inhibiting MAPK4 simultaneously inactivated both androgen receptor and AKT and stopped cancer growth in animal models.

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From The Labs 

The N-terminal domain of the androgen receptor is at the heart of its action

July 30, 2020July 30, 2020androgen receptor, C-terminal domain, coactivators, n-terminal domain, Prostate Cancer, Research, testosterone

Detailed 3-D studies reveal how the androgen receptor is put together as a functional complex that drives prostate cancer.

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From The Labs 

Making ‘sense’ of the ‘cart before the horse’ in mammalian cells

January 22, 2019January 23, 2019antisense RNA, Cancer, fusion DNA, fusion RNA, Prostate Cancer, Research, sense RNA

A fusion gene is a new gene made by joining parts of two different genes. The current thought is that fusion genes can happen in

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From The Labs 

2017 Michael E. DeBakey M.D. Award for Research Excellence

May 26, 20172017 DeBakey Award for Research Excellence, Breast Cancer, Cardiothoracic Surgery, DeBakey award, endocrine cancer, gene regulation, Neuroscience, NK cells, Norovirus, Primary immunodeficiencies, Prostate Cancer, rotavirus

The five winners of this year’s Michael E. DeBakey M.D. Award for Research Excellence exemplify the breadth and depth of scientific research at Baylor College

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From The Labs 

New oncogene MNX1 contributes to higher incidence of prostate cancer among African American men

October 12, 2016African American men, AKT, lipid metabolism, oncogene MNX1, Prostate Cancer, testosterone

Genetic factors can explain, at last in part, the higher incidence of prostate cancer among African American men compared with men of other ethnic groups.

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blue-cure-lights-featured
Momentum 

Prostate cancer: What you need to know

September 14, 2016September 9, 2019Allison Mickey, Blue Cure Foundation, Cancer, Community, Dr. Jennifer Taylor, Events, Healthcare, Houston, Men's Health, Prostate Cancer, Urology

During the month of September, Baylor College of Medicine will be partnering with the Blue Cure Foundation for its annual prostate cancer awareness campaign, Light

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From The Labs 

Altered metabolism in castration-resistant prostate cancer may point to new therapies

September 13, 2016June 23, 2020altered metabolism, Cancer, castration-resistant, hexosamine biosynthetic pathway, metabolism, Prostate Cancer, therapeutic target

Advanced prostate cancer is usually treated by removing androgen, the male hormone that helps it grow. Although initially effective, this treatment often leads to the

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From The Labs 

Mouse model shows that Notch activation can drive metastatic prostate cancer

August 23, 2016May 4, 2018Metastasis, metastatic prostate cancer, mouse model, Notch signaling pathway, Prostate Cancer, Pten gene, Research

Nearly 200 thousand men are diagnosed with prostate cancer every year. Most of the deaths associated with prostate cancer occur in advanced stages of the

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From the Labs Image of the Month

From The Labs Image of the Month From the Labs: Adult-born neurons made the cover

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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