Nuclear, not cytoplasmic CELF1, has a stronger role in muscle wasting
This work is the first to show that the response of muscle to CELF1 overexpression depends on the cellular localization of the protein.
Read moreThis work is the first to show that the response of muscle to CELF1 overexpression depends on the cellular localization of the protein.
Read moreA protein naturally produced in the body has been found to suppress breast cancer metastasis in animal models of human tumors. “Our laboratory investigates cellular
Read moreEpithelial cells line the lobules (small lobes) and terminal ducts of the breast and carry out the important function of making milk. Cancer scientists, such
Read moreImagine fighting enemies that differ in their susceptibility to the weapon you are using against them. Some will perish, but others will survive the attack
Read moreDespite the importance that changes in muscle mass have in aging, overall body metabolism and in chronic disease, we still don’t fully understand the mechanisms
Read moreMyotonic dystrophy type 1 (DM1) is the most common adult-onset muscular dystrophy that affects multiple organ systems. People with this condition develop progressive muscle wasting
Read moreFor breast cancer, expressing the protein CD44s, instead of CD44v, has a survival advantage. And one of the goals of Dr. Chonghui Cheng lab is to
Read moreCompare the skeletal muscles of a newborn with those of an adult. While the former can barely move the body, adult muscles can perform record
Read moreMyotonic dystrophy, type 1 (DM1) is the second most common cause of muscular dystrophy and numerous other muscle disorders that affect tens of thousands of
Read moreAmong other studies, the lab of Dr. Chonghiu Cheng is pioneering research projects to better undertsand the role alternative splicing plays in cancer. “We have been
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