AKAP8 and the delicate balance between normal and metastatic states
A protein naturally produced in the body has been found to suppress breast cancer metastasis in animal models of human
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alternative splicing
Image of the Month: Human breast epithelial cells
Epithelial cells line the lobules (small lobes) and terminal ducts of the breast and carry out the important function of
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CD44 variants prompt different cancer cell behaviors
Imagine fighting enemies that differ in their susceptibility to the weapon you are using against them. Some will perish, but
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Alternative splicing is crucial to muscle mass maintenance
Despite the importance that changes in muscle mass have in aging, overall body metabolism and in chronic disease, we still
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There is more going on in DM1 than just alternative splicing
Myotonic dystrophy type 1 (DM1) is the most common adult-onset muscular dystrophy that affects multiple organ systems. People with this
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G-quadruplex helps breast cancer survive
For breast cancer, expressing the protein CD44s, instead of CD44v, has a survival advantage. And one of the goals of
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Muscle’s path to maturity follows the alternative splicing way
Compare the skeletal muscles of a newborn with those of an adult. While the former can barely move the body,
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Image of the Month: What causes myotonic dystrophy, type1
Myotonic dystrophy, type 1 (DM1) is the second most common cause of muscular dystrophy and numerous other muscle disorders that
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Image of the Month: Mechanisms of cancer survival
Among other studies, the lab of Dr. Chonghiu Cheng is pioneering research projects to better undertsand the role alternative splicing plays
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CD44s, not CD44v, contributes to cancer survival
Cells may stray away from their normal function in a number of ways. For example, it’s been known for some
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