This model of DM1 allows researchers to both focus on cardiac mechanisms of the disease and to expand therapeutics to target the heart.
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This work is the first to show that the response of muscle to CELF1 overexpression depends on the cellular localization of the protein.
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A protein naturally produced in the body has been found to suppress breast cancer metastasis in animal models of human tumors. “Our laboratory investigates cellular
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Epithelial cells line the lobules (small lobes) and terminal ducts of the breast and carry out the important function of making milk. Cancer scientists, such
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Imagine fighting enemies that differ in their susceptibility to the weapon you are using against them. Some will perish, but others will survive the attack
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Despite the importance that changes in muscle mass have in aging, overall body metabolism and in chronic disease, we still don’t fully understand the mechanisms
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Myotonic dystrophy type 1 (DM1) is the most common adult-onset muscular dystrophy that affects multiple organ systems. People with this condition develop progressive muscle wasting
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For breast cancer, expressing the protein CD44s, instead of CD44v, has a survival advantage. And one of the goals of Dr. Chonghui Cheng lab is to
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Compare the skeletal muscles of a newborn with those of an adult. While the former can barely move the body, adult muscles can perform record
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Myotonic dystrophy, type 1 (DM1) is the second most common cause of muscular dystrophy and numerous other muscle disorders that affect tens of thousands of
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