Alternative splicing is crucial to muscle mass maintenance
Despite the importance that changes in muscle mass have in aging, overall body metabolism and in chronic disease, we still
Read more
alternative splicing
There is more going on in DM1 than just alternative splicing
Myotonic dystrophy type 1 (DM1) is the most common adult-onset muscular dystrophy that affects multiple organ systems. People with this
Read more
G-quadruplex helps breast cancer survive
For breast cancer, expressing the protein CD44s, instead of CD44v, has a survival advantage. And one of the goals of
Read more
Muscle’s path to maturity follows the alternative splicing way
Compare the skeletal muscles of a newborn with those of an adult. While the former can barely move the body,
Read more
Image of the Month: What causes myotonic dystrophy, type1
Myotonic dystrophy, type 1 (DM1) is the second most common cause of muscular dystrophy and numerous other muscle disorders that
Read more
Image of the Month: Mechanisms of cancer survival
Among other studies, the lab of Dr. Chonghiu Cheng is pioneering research projects to better undertsand the role alternative splicing plays
Read more
CD44s, not CD44v, contributes to cancer survival
Cells may stray away from their normal function in a number of ways. For example, it’s been known for some
Read more
How do muscles grow up? Check alternative splicing
Growing up is a complex affair, even for muscles. In the mouse, for instance, newborn muscles grow into adult muscles
Read more