CD44 variants prompt different cancer cell behaviors
Imagine fighting enemies that differ in their susceptibility to the weapon you are using against them. Some will perish, but others will survive the attack
Read More
Metastasis
An integrated approach to finding new treatments for breast cancer
Unraveling the complexity of cancer biology can lead to the identification new molecules involved in breast cancer and prompt new avenues for drug development. And
Read More
Estrogen receptor can affect resistance to endocrine therapy and metastasis in breast cancer
Resistance to therapy is common in estrogen receptor positive (ER+) breast cancer, the most common type of breast cancer, and eventual development of metastatic disease
Read More
This is what the Warburg pathway can do for breast cancer growth
To generate energy from glucose, cells can use one of two pathways. One of them takes place in the mitochondria, energy-producing structures inside cells, and
Read More
Device that induces a mild localized ‘fever’ could treat vascular involvement in cancer
The prognosis of a cancer patient relies significantly on the ability of the surgeon to remove all the tumor, including a cancer-free boundary, leaving what
Read More
Out of the body and into bone-in culture: new technique tests drugs for metastatic cancer
For many cancer patients, the problem is metastasis – the dissemination of tumor cells to other organs – after the primary tumor has been eliminated.
Read More
How breast cancer can become resistant to hormone therapy
Despite the overall success of hormone therapy, breast cancer tumors in patients with metastatic disease often fail to respond. One new mechanism that can explain
Read More
Mouse model shows that Notch activation can drive metastatic prostate cancer
Nearly 200 thousand men are diagnosed with prostate cancer every year. Most of the deaths associated with prostate cancer occur in advanced stages of the
Read More