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From The Labs

IMAGE OF THE MONTH: The finite nature of brain regeneration

August 1, 2019 Alzheimer's Disease,  neuroregeneration,  non-convulsive seizures,  Research

ON THE COVER! The finite nature of brain regeneration. Image by Jeannie Chin. In normal mice, neurogenesis occurs throughout life and decreases as the animals

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From The Labs

Connecting seizures, neurogenesis and cognitive functions in Alzheimer’s disease

July 18, 2019 Alzheimer's Disease,  neurogenesis,  Research,  seizures

Whether the normal adult human brain produces new neurons, much less those with Alzheimer’s disease, is a controversial topic in the field. While some groups

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From The Labs

Understanding the cell waste disposal problems in Lou Gehrig’s disease

March 12, 2019 ALS,  Alzheimer's Disease,  autophagy,  Drosophila,  fruit fly,  Lou Gehrig's disease,  lysosomes,  proteasome,  Research,  ubiquilin

Building up cellular waste is bad news for cells, and particularly for neurons. Such excessive build up can lead to neurological conditions, as is the

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From The Labs

Beyond the airway and into the brain, yeast impairs memory in mice

January 31, 2019 airway disease,  Allergies,  Alzheimer's Disease,  C. albicans,  Dementia,  FIGG,  fungal infection,  fungus,  sepsis,  yeast

An increasing number of clinical observations indicates that fungi are becoming a more common cause of upper airway allergic diseases such as asthma, as well

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Momentum

Dementia and Alzheimer’s disease: What you need to know

October 23, 2018 Alzheimer's Disease,  Dementia,  Dr. Mark Kunik,  Geriatrics,  Healthcare,  Nicole Blanton,  Psychiatry

There are many concerns associated with aging, including issues with memory or cognitive decline. You may hear the terms dementia and Alzheimer’s disease used interchangeably

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From The Labs

Connecting Tau aggregates, transposable elements and neurodegeneration in Alzheimer’s disease

August 2, 2018 Alzheimer's Disease,  genomic instability,  neurlogic diseases,  Neurodegeneration,  Research,  tau,  transposable elements

Although it’s been known for years that the accumulation of Tau protein within brain cells in combination with progressive cell death is one of the

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From The Labs

Two is better than one, to improve brain function on a mouse model of Alzheimer’s disease

April 24, 2018 Alzheimer's Disease,  amyloid-beta,  mouse model,  mTOR,  Research

Many of the therapies that are currently being developed to treat Alzheimer’s disease focus on reducing the levels of amyloid-beta, a small protein that is

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From The Labs

When protein regulators go awry, neurological disease may follow

April 19, 2018 Alzheimer's Disease,  Ataxin1,  Mouse models,  neurological disease,  PUMILIO1,  Research,  SCA1

Scientists are expanding their horizons in their search for disease-causing genes. Consider for instance a neurological condition called spinocerebellar ataxia type 1 (SCA1), a disease

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From The Labs

How infrequent seizures may lead to persistent memory loss in Alzheimer’s disease

January 10, 2018 Alzheimer's Disease,  calbindin,  deltaFosB,  epilepsy,  epileptic seizures,  hippocampus,  memory loss

Even relatively infrequent seizures can lead to long-lasting cognitive deficits in animal models of Alzheimer’s disease; how this happens, however, has been difficult to explain.

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From The Labs

Breakdown of neuron-glia partnership can pave the way to neurodegeneration

November 30, 2017 Alzheimer's Disease,  APOE4,  free radicals,  glia cells,  lipid accumulation,  Neurodegeneration,  neuron

In 2015, Dr. Lucy Liu, now a Ph.D. graduate in neuroscience from the Bellen lab, discovered that a number of genes involved in neurodegeneration promote

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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