Brain sphingolipid metabolism is closely involved in Gaucher disease
Disruption of sphingolipid metabolism led to neurodegeneration in animal models, revealing a new molecular path to Gaucher’s disease.
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lysosomes
Talking about aging, lysosomes have something to say
The new findings help us understand how longevity is regulated at a whole organism level.
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New insights into the fate of dying cells
The Zhou lab reveals a new player in the elimination of dying cells and identifies a mechanism for the process.
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Image of the Month: Art meets science to visualize the fruit fly’s brain
Studying the brain of the fruit fly helps understand the human brain, both in health and disease. Working in the lab of
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Understanding the cell waste disposal problems in Lou Gehrig’s disease
Building up cellular waste is bad news for cells, and particularly for neurons. Such excessive build up can lead to neurological conditions, as is the
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Tuberous sclerosis: it’s not all about mTORC1
mTORC1, a protein complex that regulates cell metabolism, has long been considered the major driving force behind tuberous sclerosis. New experimental evidence, however, is challenging
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A worm’s lessons for living a longer, healthier life
Caenorhabditis elegans is a seemingly unimpressive worm. It is as long as a penny is thick, it lives in the soil feeding on microbes it
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Juvenile Batten disease, a problem with cellular waste management
Like a large dynamic city, a cell carries out many activities that generate waste. Waste needs to be disposed of properly in order for the
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