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epileptic seizures

From The Labs

How infrequent seizures may lead to persistent memory loss in Alzheimer’s disease

January 10, 2018May 29, 2019Alzheimer's Disease, calbindin, deltaFosB, epilepsy, epileptic seizures, hippocampus, memory loss

Even relatively infrequent seizures can lead to long-lasting cognitive deficits in animal models of Alzheimer’s disease; how this happens, however, has been difficult to explain.

From The Labs

‘Silent seizures’ discovered in patients with Alzheimer’s disease

July 10, 2017Alzheimer's Disease, deep brain, eeg, epilepsy, epileptic seizures, hippocampus, nonconvulsive seizures, seizures

Deep in the brains of two patients with Alzheimer’s disease, the main memory structure, the hippocampus, displays episodic seizure-like electrical activity. These nonconvulsive hippocampal seizures

From the Labs: Microscopy image of a brain region that coordinates survival adaptations to food shortages. Image courtesy of the authors/Cell Reports, 2021.