Mouse models Archives - Baylor College of Medicine Blog Network

The power of the microbiome: A microbe-based treatment reverses social deficits in mouse models of autism

December 13, 2018December 13, 2018 autism spectrum disorders, L. reuteri, microbial-based treatment, microbiome, Mouse models, Research, social deficits

An unconventional bacteria-based approach has successfully reversed deficits in social behaviors associated with autism spectrum disorders (ASD) in genetic, environmental and idiopathic mouse models of

From The Labs

When protein regulators go awry, neurological disease may follow

April 19, 2018April 27, 2018 Alzheimer's Disease, Ataxin1, Mouse models, neurological disease, PUMILIO1, Research, SCA1

Scientists are expanding their horizons in their search for disease-causing genes. Consider for instance a neurological condition called spinocerebellar ataxia type 1 (SCA1), a disease

From The Labs

Mouse blood vessels and immune system can team up against cancer metastasis

May 19, 2017 angiogenesis, anti-blood vessel therapy, Breast Cancer, Breast cancer microenvironment, Immunotherapy, Mouse models, T cells, vessel normalization

Picture a shapeless, small mass of tumor cells inside an otherwise healthy organ. The tumor is growing, thanks, among other things, to its ability to

From The Labs

Of mice, men and proteasomes; OTUD6B variant causes intellectual and physical disability

May 3, 2017 developmental disorders, Human genetics, intellectual disabilities, Mouse models, OTUD6B, physical disabilities, proteasome, whole exome sequencing

One of Dr. Magdalena Walkiewicz’s patients had not received a genetic diagnosis for his condition that included a number of intellectual and physical disabilities. After

From The Labs

From mouse model to human; serendipity leads to human genetic diagnosis

April 24, 2017 ATXN1-CIC, Autism, developmental delay, epilepsy, hyperactivity, intellectual disabilitis, Mouse models, Neuroscience

When Dr. Huda Zoghbi and her colleagues were investigating the role protein complex ATXN1-CIC plays in the normal development of the mouse brain they did not