autophagy Archives - Baylor College of Medicine Blog Network

Studying the brain of the fruit fly helps understand the human brain, both in health and disease. Working in the lab of

Understanding the cell waste disposal problems in Lou Gehrig’s disease

March 12, 2019March 12, 2019ALS, Alzheimer's Disease, autophagy, Drosophila, fruit fly, Lou Gehrig's disease, lysosomes, proteasome, Research, ubiquilin

Building up cellular waste is bad news for cells, and particularly for neurons. Such excessive build up can lead to neurological conditions, as is the

From The Labs

A potential new purpose for an old drug

November 20, 2018November 27, 2018autophagy, flunarizine, Ras, Research, triple-negative breast cancer

When it comes to finding new drugs to treat breast cancer, some scientists are taking an approach that could expedite the discovery of new treatments.

From The Labs

Thinking outside the box to fight back neurodegeneration

August 28, 2018August 30, 2018autophagy, lysosome disease, MPS IIIB, mucopolysaccharidoses IIIB, Neurodegeneration, Research, TFEB, trehalose

Neurodegeneration in a disease called mucopolysaccharidoses IIIB (MPS IIIB) results from the abnormal accumulation of essential molecules called mucopolysaccharides. In his lab at Baylor College

From The Labs

A new approach to potentially treat Huntington’s disease

February 13, 2018February 13, 2018autophagy, huntingtin, Huntington’s disease, lysosome storage disorder, NCT-504, PIP4Kgamma, PIP4Kγ

In Huntington’s disease, a single faulty gene called huntingtin causes a progressive breakdown of nerve cells in the brain and severe physical and neurological damage

From The Labs

Autophagy: Protector against lung inflammation and fibrosis

June 15, 2015autophagy, Genetics, lungs, pulmonary fibrosis, sepsis

By Ruth SoRelle, M.P.H. When bacteria or viruses invade the body, a process called autophagy, or “self-eating,” springs into action to take the invaders to