proteasome Archives - Baylor College of Medicine Blog Network

Studying the brain of the fruit fly helps understand the human brain, both in health and disease. Working in the lab of

Understanding the cell waste disposal problems in Lou Gehrig’s disease

March 12, 2019March 12, 2019ALS, Alzheimer's Disease, autophagy, Drosophila, fruit fly, Lou Gehrig's disease, lysosomes, proteasome, Research, ubiquilin

Building up cellular waste is bad news for cells, and particularly for neurons. Such excessive build up can lead to neurological conditions, as is the

From The Labs

USP15 could be a target in ovarian cancer scientists have been looking for

May 8, 2018May 8, 2018lysosome, ovarian cancer, ovarian steroids, p53, p53-R175H, proteasome, Research, steroid receptor coactivator, USP 15

Ovarian cancer is currently treated with surgery and chemotherapy. Chemotherapy for ovarian cancer is based on drugs that act on any cell that is rapidly

From The Labs

Of mice, men and proteasomes; OTUD6B variant causes intellectual and physical disability

May 3, 2017developmental disorders, Human genetics, intellectual disabilities, Mouse models, OTUD6B, physical disabilities, proteasome, whole exome sequencing

One of Dr. Magdalena Walkiewicz’s patients had not received a genetic diagnosis for his condition that included a number of intellectual and physical disabilities. After