PBRM1’s new function supports a novel cancer-promoting mechanism
New findings suggest that cancer-associated defects in chromatin remodeler genes can drive cancer by disrupting cytoskeletal activities.
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genomic instability
Identifying rare genetic variants that increase risk for lung cancer
Exome sequencing identified new variants that lead to higher levels of DNA damage, which increases the susceptibility for multiple cancers.
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Connecting Tau aggregates, transposable elements and neurodegeneration in Alzheimer’s disease
Although it’s been known for years that the accumulation of Tau protein within brain cells in combination with progressive cell death is one of the
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