Image of the Month: Brain of a mouse model of Huntington’s Disease
This confocal microscopy image shows a section of the brain of a mouse model of Huntington’s disease, with the astrocytes in green and cell nuclei in blue.
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mouse model
Focused on the Heart — Novel mouse model of myotonic dystrophy displays reversible cardiac disease features of the condition
This model of DM1 allows researchers to both focus on cardiac mechanisms of the disease and to expand therapeutics to target the heart.
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A steady supply of sugar is good news for colorectal cancer
The current thought is that sugar is harmful to our health mainly because consuming too much can lead to obesity. Research shows that obesity increases
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The dark side of antibiotic ciprofloxacin
UPDATE: A few months after this article was posted, the work by Baylor researchers has begun to have international impact. Read the details here. The use
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Image of the Month: SCA1-like neurodegeneration
In a mouse model of spinocerebellar ataxia type 1 (SCA1), mice carrying mutant Pumilio1 genes develop progressive motor deficits and cerebellar degeneration. Studies conducted by the
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Two is better than one, to improve brain function on a mouse model of Alzheimer’s disease
Many of the therapies that are currently being developed to treat Alzheimer’s disease focus on reducing the levels of amyloid-beta, a small protein that is
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Mouse model helps solve 15q13.3 microdeletion puzzle
Individuals with a complex neurological condition called 15q13.3 microdeletion syndrome are missing a small piece of chromosome 15 that usually contains six genes. Although this
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Tapping on the healing capacity of the heart
If your skin is injured, it can heal itself. If you lose blood, your body makes more. If a lobe is removed from a mouse
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It’s all connected: circadian clock, microbiome and response to diet
Disrupt the circadian clock, and metabolism will change. Alter the microbiome and, again, metabolism will change. Would altering the circadian clock affect the microbiome? Dr.
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CRKL in 22q11.2; a key gene that contributes to common birth defects
The 22q11.2 region of human chromosome 22 is a hotspot for a variety of birth defects. Scientists learned about this region because it is deleted in
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