mouse model

From The Labs 

A steady supply of sugar is good news for colorectal cancer

March 28, 2019March 28, 2019 Ana Rodríguez 0 Comments APC gene, Colorectal Cancer, FASN, fructose, KHK, mouse model, Research, sweet drinks

The current thought is that sugar is harmful to our health mainly because consuming too much can lead to obesity.

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From The Labs 

The dark side of antibiotic ciprofloxacin

July 25, 2018October 30, 2018 Ana Rodríguez 1 Comment antibiotics, aorta tears and ruptures, aortic aneurysms and dissections, ciprofloxacin, extracellular matrix, fluoroquinolones, mouse model, Research

UPDATE: A few months after this article was posted, the work by Baylor researchers has begun to have international impact. Read

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From The Labs 

Image of the Month: SCA1-like neurodegeneration

May 1, 2018May 1, 2018 Ana Rodríguez 0 Comments ataxia, mouse model, Neurodegeneration, pumilio, Purkinje cells, Research, spinocerebellar ataxia type 1

In a mouse model of spinocerebellar ataxia type 1 (SCA1), mice carrying mutant Pumilio1 genes develop progressive motor deficits and cerebellar

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From The Labs 

Two is better than one, to improve brain function on a mouse model of Alzheimer’s disease

April 24, 2018April 27, 2018 Ana Rodríguez 0 Comments Alzheimer's Disease, amyloid-beta, mouse model, mTOR, Research

Many of the therapies that are currently being developed to treat Alzheimer’s disease focus on reducing the levels of amyloid-beta,

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From The Labs 

Mouse model helps solve 15q13.3 microdeletion puzzle

March 22, 2018April 27, 2018 Ana Rodríguez 0 Comments 15q13.3 microdeletion syndrome, dendritic spines, mouse model, neurodevelopmental disorder, OTUD7A, Research

Individuals with a complex neurological condition called 15q13.3 microdeletion syndrome are missing a small piece of chromosome 15 that usually

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From The Labs 

Tapping on the healing capacity of the heart

January 5, 2018February 5, 2018 Ana Rodríguez 0 Comments Heart disease and regeneration, heart failure, Hippo pathway, injured heart, mouse model, regeneration

If your skin is injured, it can heal itself. If you lose blood, your body makes more. If a lobe

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From The Labs 

It’s all connected: circadian clock, microbiome and response to diet

June 30, 2017 Ana Rodríguez 0 Comments circadian clock, diet, metabolism, microbiome, mouse model, Npas2 gene

Disrupt the circadian clock, and metabolism will change. Alter the microbiome and, again, metabolism will change. Would altering the circadian

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From The Labs 

CRKL in 22q11.2; a key gene that contributes to common birth defects

May 24, 2017 Ana Rodríguez 0 Comments 22q11.2, Birth defects, CRKL, cryptorchidism, DiGeorge syndrome, Genetics, genitourinary birth defects, hypospadias, kidney birth defects, mouse model

The 22q11.2 region of human chromosome 22 is a hotspot for a variety of birth defects. Scientists learned about this

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From The Labs 

Changes in NLRP genes may be an answer to unexplained female infertility

April 28, 2017 Ana Rodríguez 1 Comment Fertility, in vitro fertilization, infertility gene, mouse model, NLRP genes

Scientists estimate that as many as 15 percent of couples with infertility and 50 percent of women with recurrent pregnancy

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From The Labs 

A pill to prevent Alzheimer’s disease might someday be a reality

January 18, 2017 Ana Rodríguez 0 Comments Alzheimer's Disease, fruit fly model, Genetics, mouse model, Nuak1, Parkinson's Disease, tau

Taking a pill that prevents the accumulation of toxic molecules in the brain might someday help prevent or delay Alzheimer’s

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