BICRA gene variants linked to a neurodevelopmental disorder
Genetic testing of an undiagnosed condition triggered a study that linked the BICRA to a neurodevelopmental disorder.
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fruit fly
‘Rule-breakers’ help identify novel gene variants that modify risk of late-onset Alzheimer’s disease
Using novel methodologies, researchers identified 216 new gene variants, many previously not suspected to play a role in Alzheimer’s disease.
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Image of the Month: Nervous tissue of the fruit fly embryo
The fruit fly is a valuable animal model to unravel the genetic causes of both rare and more common human diseases. This Image of the
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New undiagnosed disease linked to variants of WDR37 gene
A new undiagnosed neurological syndrome that is characterized by brain malformations and a range of symptoms including visual impairment, epilepsy, developmental delays and intellectual disability
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Image of the Month: Art meets science to visualize the fruit fly’s brain
Studying the brain of the fruit fly helps understand the human brain, both in health and disease. Working in the lab of
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Understanding the cell waste disposal problems in Lou Gehrig’s disease
Building up cellular waste is bad news for cells, and particularly for neurons. Such excessive build up can lead to neurological conditions, as is the
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Image of the Month: Snapshot of eye development in the fruit fly
In his lab at Baylor College of Medicine, Dr. Hugo Bellen and his colleagues work with the fruit fly, Drosophila melanogaster, as a model system
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There are new key players in Parkinson’s disease
The roadmap that may lead to Parkinson’s disease has a number of ‘landmarks,’ gene variants and cellular defects known to be associated with the disease.
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Sorting out what drives Huntington’s disease
Neurological diseases are typically associated with a multitude of molecular changes. But out of thousands of changes in gene expression, which ones are actually driving
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Of fruit flies, genes and aortic aneurysms
One of the goals of Dr. Hugo Bellen’s lab is to conduct genetic screens in the fruit fly to identify genes that cause neurodevelopmental and
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