Solving the puzzle of Mitchell disease
When a patient with puzzling neurological symptoms enrolled in the Undiagnosed Diseases Network, researchers led by Dr. Hugo J. Bellen were set on solving the
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Neurodegeneration
The 2019 Michael E. DeBakey M.D. Awards for Excellence in Research
The 2019 Michael E. DeBakey M.D. Award for Research Excellence ceremony honored five Baylor College of Medicine faculty members for their excellence in published scientific
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There are new key players in Parkinson’s disease
The roadmap that may lead to Parkinson’s disease has a number of ‘landmarks,’ gene variants and cellular defects known to be associated with the disease.
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Thinking outside the box to fight back neurodegeneration
Neurodegeneration in a disease called mucopolysaccharidoses IIIB (MPS IIIB) results from the abnormal accumulation of essential molecules called mucopolysaccharides. In his lab at Baylor College
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Connecting Tau aggregates, transposable elements and neurodegeneration in Alzheimer’s disease
Although it’s been known for years that the accumulation of Tau protein within brain cells in combination with progressive cell death is one of the
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Image of the Month: SCA1-like neurodegeneration
In a mouse model of spinocerebellar ataxia type 1 (SCA1), mice carrying mutant Pumilio1 genes develop progressive motor deficits and cerebellar degeneration. Studies conducted by the
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How disrupting mitochondria genes can lead to neurodegeneration
Years back, the Bellen lab identified many mutations in genes of the mitochondria, the energy generators of the cell. Among them was a mutation in
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Breakdown of neuron-glia partnership can pave the way to neurodegeneration
In 2015, Dr. Lucy Liu, now a Ph.D. graduate in neuroscience from the Bellen lab, discovered that a number of genes involved in neurodegeneration promote
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