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mucopolysaccharidoses IIIB

From The Labs

Thinking outside the box to fight back neurodegeneration

August 28, 2018August 30, 2018 Ana Rodríguez 0 Comments autophagy, lysosome disease, MPS IIIB, mucopolysaccharidoses IIIB, Neurodegeneration, Research, TFEB, trehalose

Neurodegeneration in a disease called mucopolysaccharidoses IIIB (MPS IIIB) results from the abnormal accumulation of essential molecules called mucopolysaccharides. In his lab at Baylor College

From the Labs Image of the Month

From the Labs features an image pinpointing the location of Man1b1 inside the cell, which sharpened the view of cellular regulation of protein homeostasis. Image courtesy of the Sifers lab/Molecular Biology of the Cell, 2011.