A novel strategy to suppress prostate cancer growth
The researchers took a close look into what drives the growth of advanced tumors that have become resistant to standard castration therapy.
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androgen receptor
Targeting MAPK4 emerges as a promising therapy for prostate cancer
Inhibiting MAPK4 simultaneously inactivated both androgen receptor and AKT and stopped cancer growth in animal models.
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The N-terminal domain of the androgen receptor is at the heart of its action
Detailed 3-D studies reveal how the androgen receptor is put together as a functional complex that drives prostate cancer.
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