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androgen receptor

From The Labs

Targeting MAPK4 emerges as a promising therapy for prostate cancer

February 23, 2021February 23, 2021 Ana Rodríguez 0 Comments Akt pathway, androgen receptor, cancer therapy, castration-resistant prostate cancer, MAPK4, Prostate Cancer, Research

Inhibiting MAPK4 simultaneously inactivated both androgen receptor and AKT and stopped cancer growth in animal models.

From The Labs

The N-terminal domain of the androgen receptor is at the heart of its action

July 30, 2020July 30, 2020 Ana Rodríguez 0 Comments androgen receptor, C-terminal domain, coactivators, n-terminal domain, Prostate Cancer, Research, testosterone

Detailed 3-D studies reveal how the androgen receptor is put together as a functional complex that drives prostate cancer.

From the Labs features an image of endothelial cells of the bovine pulmonary artery. Image courtesy of J. Kirk/ Baylor's Optical Imaging & Vital Microscopy Core Lab.