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From The Labs

Studying gene function is now easier, faster and more efficient

September 28, 2021 drug-based selection and counterselection,  fruit fly,  gene function,  genetic studies,  Research

A drug-based genetic platform enables scientists to follow genetic manipulations in the laboratory fruit fly more efficiently.

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From The Labs

BICRA gene variants linked to a neurodevelopmental disorder

January 14, 2021 BICRA gene,  Coffin-Siris syndrome,  fruit fly,  neurodevelopmental disease,  neurodevelopmental disorder,  Research,  zebra fish

Genetic testing of an undiagnosed condition triggered a study that linked the BICRA to a neurodevelopmental disorder.

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From The Labs

‘Rule-breakers’ help identify novel gene variants that modify risk of late-onset Alzheimer’s disease

January 12, 2021 ADSP,  APOE,  fruit fly,  genetic risk,  Late-onset Alzheimer’s disease,  Research

Using novel methodologies, researchers identified 216 new gene variants, many previously not suspected to play a role in Alzheimer’s disease.

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From The Labs

Image of the Month: Nervous tissue of the fruit fly embryo

January 7, 2020 fruit fly,  IQSEC1,  neurodegenerative disorders,  rare disease,  Research,  schizo

The fruit fly is a valuable animal model to unravel the genetic causes of both rare and more common human diseases. This Image of the

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From The Labs

New undiagnosed disease linked to variants of WDR37 gene

August 13, 2019 fruit fly,  neurological disease,  Research,  undiagnosed diseases,  WDR37

A new undiagnosed neurological syndrome that is characterized by brain malformations and a range of symptoms including visual impairment, epilepsy, developmental delays and intellectual disability

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From The Labs

Image of the Month: Art meets science to visualize the fruit fly’s brain

April 2, 2019 ALS,  autophagy,  fruit fly,  Lou Gehrig's disease,  lysosomes,  proteasome,  rare disease,  reseach,  ubiquilin

Studying the brain of the fruit fly helps understand the human brain, both in health and disease.       Working in the lab of

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From The Labs

Understanding the cell waste disposal problems in Lou Gehrig’s disease

March 12, 2019 ALS,  Alzheimer's Disease,  autophagy,  Drosophila,  fruit fly,  Lou Gehrig's disease,  lysosomes,  proteasome,  Research,  ubiquilin

Building up cellular waste is bad news for cells, and particularly for neurons. Such excessive build up can lead to neurological conditions, as is the

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From The Labs

Image of the Month: Snapshot of eye development in the fruit fly

November 1, 2018 congenital bilateral cataracts,  DNMBP,  Drosophila,  fruit fly,  Research

In his lab at Baylor College of Medicine, Dr. Hugo Bellen and his colleagues work with the fruit fly, Drosophila melanogaster, as a model system

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From The Labs

There are new key players in Parkinson’s disease

August 30, 2018 alpha-synuclein,  ceramide,  fruit fly,  Neurodegeneration,  Parkinson's Disease,  phospholipase PLA2G6,  Research,  retromer

The roadmap that may lead to Parkinson’s disease has a number of ‘landmarks,’ gene variants and cellular defects known to be associated with the disease.

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From The Labs

Sorting out what drives Huntington’s disease

July 12, 2018 fruit fly,  high-throughput,  huntingtin,  Huntington’s disease,  neurological disease,  Research

Neurological diseases are typically associated with a multitude of molecular changes. But out of thousands of changes in gene expression, which ones are actually driving

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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