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From The Labs

From my perspective: Dr. Joshua Adams shares his experiences in Baylor College of Medicine’s M.D./Ph.D. program

October 24, 2019 Alagille syndrome,  MD/PhD program,  Research

From the Labs interviewed Dr. Joshua M. Adams to learn about his experiences during his training in Baylor College of Medicine‘s M.D./Ph.D. program. He has

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From The Labs

IQSEC1 gene mutations cause new intellectual disability syndrome

October 22, 2019 consanguineous marriages,  intellectual disability,  IQSEC1,  Research,  schizo gene

It used to take several years or sometimes decades to unequivocally identify the genes that cause rare human syndromes that affect very few individuals. Nowadays,

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From The Labs

When tau tangles, RNA errors can happen in Alzheimer’s disease

October 17, 2019 Alzheimer's Disease,  Research,  RNA splicing errors,  spliceosome,  tau protein,  tau tangles

The tau protein is a key player in Alzheimer’s disease. It tangles and accumulates inside brain cells and this, in combination with increasing cell death,

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From The Labs

What the Hippo pathway in cardiac fibroblasts reveals about heart function

October 15, 2019 cardiac fibroblasts,  cardiomyocytes,  heart attack,  heart regeneration,  Hippo pathway,  Research,  YAP

Heart failure remains the leading cause of mortality in the U.S. During a heart attack, blood stops flowing into the heart. Without oxygen, part of

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From The Labs

Sox9 reshapes the biliary tree in Alagille syndrome

October 10, 2019 Alagille syndrome,  bile,  bile tree,  cholestasis,  intrahepatic bile ducts,  JAG1,  liver,  Notch signaling,  Research,  SOX9

Alagille syndrome is a rare pediatric genetic disorder that can affect the liver, heart, kidneys, blood vessels, skeleton and other tissues. One major characteristic of

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From The Labs

ON A MATTER OF HEALTH: Clinical trial tests novel treatment strategy for ITP

October 8, 2019 bleeding,  blood clot,  clinical trial,  eltrombopag,  immune thrombocytopenia,  ITP

The immune system is meant to protect the body from foreign invaders. A rare condition called immune thrombocytopenia (ITP) occurs when the body’s defense system

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From The Labs

Exploring the stress-mood-appetite connection

October 3, 2019 appetite,  dopamine,  hypothalamus,  Mood,  POMC neurons,  Research,  Stress

Does stress affect your appetite or your mood? Many people have experienced stressful situations that trigger a particular mood and also change certain feelings toward

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From The Labs

Image of the Month: Islet of Langerhans

October 1, 2019 Diabetes,  DNA methylation,  epigenetics,  insulin,  Islet of Langerhans,  overnutrition,  Research

Cells of the Islets of Langerhans in the pancreas help regulate blood sugar. Disrupting their normal function can contribute to the development of diabetes. The

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From The Labs

The unexpected functional diversity of reactive astrocytes

September 26, 2019 astrocytes,  brain injury,  brain repair,  NFIA,  Research,  thrombospondin 4

When the brain is injured or diseased astrocytes are the first to respond. They become reactive and play roles that can be both beneficial and

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From The Labs

Exploring the risk of ALL in children with Down syndrome

September 24, 2019 Acute Lymphoblastic Leukemia,  ALL,  CDKN2A gene,  Childhood leukemia,  Down syndrome,  IKZF1 gene,  Research

Acute Lymphoblastic Leukemia (ALL) is the most common childhood cancer. Children with trisomy 21 (Down syndrome) are 10 to 20 times more likely to develop ALL

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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