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misfolded proteins

The road to uncovering a novel mechanism for disposing of misfolded proteins

October 20, 2020 alpha1-antitrypsin (AAT) deficiency, conformational diseases, liver deficiency, lung disease, Man1b1, misfolded proteins, Neurodegeneration, Research

The discovery of the cause of a rare liver disease in babies may lead to preventing more common neurological disorders occurring in late age.

To be or not to be in the ER, that is the question

August 25, 2020 BMP4, endoplasmic reticulum, ERAD, misfolded proteins, NGLY1, proteasomal degradation, Research

Researchers discovered a new way cells can dispose of misfolded proteins that may help better understand human NGLY1 deficiency.

From the Labs Image of the Month:

From the Labs: Human retinal organoid.

Healthy Habits: A DOC-umentary Series

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