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conformational diseases

From The Labs

The right place of human Man1b1

November 3, 2020November 4, 2020 Ana Rodríguez 0 Comments conformational diseases, Image of the month, Man1b1, Research

Pinpointing the location of Man1b1 inside the cell sharpened the view of cellular regulation of protein homeostasis.

From The Labs

The road to uncovering a novel mechanism for disposing of misfolded proteins

October 20, 2020October 20, 2020 Ana Rodríguez 0 Comments alpha1-antitrypsin (AAT) deficiency, conformational diseases, liver deficiency, lung disease, Man1b1, misfolded proteins, Neurodegeneration, Research

The discovery of the cause of a rare liver disease in babies may lead to preventing more common neurological disorders occurring in late age.

From the Labs features an image pinpointing the location of Man1b1 inside the cell, which sharpened the view of cellular regulation of protein homeostasis. Image courtesy of the Sifers lab/Molecular Biology of the Cell, 2011.