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From The Labs

A year in pictures

December 21, 2017 Image of the month,  research at Baylor College of Medicine

From the Labs closes 2017 with an Image of the Month photo album that highlights research at Baylor College of Medicine.   Happy holidays!  

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From The Labs

Friend and foe: Histamine mediates allergies and can fight colorectal cancer

December 19, 2017 Allergies,  Colorectal Cancer,  histamine,  histidine decarboxylase,  inflammation,  L. reuteri,  probiotics,  tumor growth,  tumorigenesis

Previous studies have shown that histamine is not only involved in allergic disease, it also may have a potential antitumor effect. At Baylor College of

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From The Labs

What matters the most to cells

December 14, 2017 DNA biology,  DNA repair,  DNA transcription,  E. Coli,  eXOnucleases sequencing,  fidelity of transcription,  GreA,  protein synthesis,  RNA

“If you asked a group of scientists which is more important for a cell, maintaining the integrity of its DNA containing all of the organism’s

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From The Labs

Atoh1, a potential Achilles’ heel of Sonic Hedgehog MB

December 12, 2017 Atoh1,  brain cancer,  brain tumor in children,  Cerebellum,  Jak2,  medulloblastoma,  Sonic Hedgehog,  Tyrosine 78

Medulloblastoma is the most common type of solid brain tumor in children. Current treatments offer limited success and may leave patients with severe neurological side

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From The Labs

DNA loops matter for NFIA gene expression in brain tumors

December 7, 2017 3-D DNA loops,  brain cancer,  DNA architecture,  DNA loops,  enhancers,  gene regulation,  Glioma,  NFIA,  transcription factors

The nuclear factor I-A (NFIA) gene is important for both normal brain development and brain tumor growth. One way to discover paths that can lead

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From The Labs

Image of the Month: Top Three Most Viewed Images of the Month, 2017

December 5, 2017 Batten disease,  C. elegans,  lipid droplets,  tumor blood vessels

Each month, From the Labs posts an image representative of research conducted at Baylor College of Medicine. These three are the most viewed images of

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From The Labs

Breakdown of neuron-glia partnership can pave the way to neurodegeneration

November 30, 2017 Alzheimer's Disease,  APOE4,  free radicals,  glia cells,  lipid accumulation,  Neurodegeneration,  neuron

In 2015, Dr. Lucy Liu, now a Ph.D. graduate in neuroscience from the Bellen lab, discovered that a number of genes involved in neurodegeneration promote

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From The Labs

How having too much or too little of CHRNA7 can lead to neuropsychiatric disorders

November 28, 2017 Autism,  calcium channel,  cellular stress,  CHRNA7,  cognitive impairment,  genetic condition,  Genetics,  Human genetics,  neuron,  Neuropsychiatric disorders,  neuropsychiatric disordrs

Studying the genetic code allows researchers to know whether some patients with neuropsychiatric disorders either have extra copies of the CHRNA7 gene or are missing

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From The Labs

Analyzing cryo-electron tomography images just got faster

November 22, 2017 annotated 3D structures,  Cryo-electron tomography,  microscopy methods,  neuronal networks

Researchers use cryo-electron tomography to visualize macromolecules frozen in action and details of structures inside of cells. This method provides 100 times better resolution than

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From The Labs

How estrogen regulates gene expression

November 20, 2017 CARM1,  coactivators,  endocrinology,  ER-alpha,  estrogen,  hormone action,  p300,  SRC-3B

Estrogens are a group of hormones that are essential for normal female sexual development and for the healthy functioning of the reproductive system. They also

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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