A new mechanism of cisplatin resistance in cancer, and how to reverse it
ACLT6A overexpression confers cancer cells resistance to cisplatin, and researchers found a way to reverse it.
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DNA repair
Identifying rare genetic variants that increase risk for lung cancer
Exome sequencing identified new variants that lead to higher levels of DNA damage, which increases the susceptibility for multiple cancers.
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Exceptional responders reveal cancer’s Achilles heel
Genome sequencing analysis of biopsied tumors points at genetic explanations for exceptional responses to therapeutics.
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When DNA is caught at the break
Cells have in place a number of mechanisms to protect the integrity of the genome, including processes that repair mistakes that may occur during DNA
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What matters the most to cells
“If you asked a group of scientists which is more important for a cell, maintaining the integrity of its DNA containing all of the organism’s
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“Freeze-frame” synthetic proteins capture DNA events leading to cancer
Cancer scientists have focused on identifying signature genetic changes present in cancerous cells and understanding how these changes lead to cancer. Although this approach has
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