heart failure Archives - Baylor College of Medicine Blog Network

A stethoscope with a bright red heart sitting next to it.

Michael Sheehan provides an overview of the many conditions that fall under heart failure and describes some treatment methods.

From The Labs

The circadian clock in heart failure

February 3, 2022February 3, 2022 chronotherapy, circadian clock, fat metabolism, heart failure, obesity paradox, Research, Rev-erbα/β, sugar metabolism

Disrupting the rhythm of molecular clock protein Rev-erbα/β leads to heart failure in animal models.

From The Labs

Innovative approach brings cell-reprogramming therapy for heart failure closer to reality

January 6, 2022January 7, 2022 cardiomyocyte, cell reprogramming, endothelial cell, fibroblast, heart failure, Research

A new cell reprogramming strategy can change large scar tissue in rat hearts into working muscle.

From The Labs

New research moves novel gene therapy for heart failure closer to the clinic

July 20, 2021July 20, 2021 cardiomyocytes, gene therapy, heart attack, heart failure, heart repair, Hippo pathway, Research

Knocking down the Hippo signaling pathway in pig cardiomyocytes after a heart attack, resulted in heart tissue renewal and improved function.

From The Labs

MCB-613 helps the heart heal itself after a heart attack

December 17, 2020December 17, 2020 heart attack, heart failure, heart repair and regeneration, MCB-613, Research, SRC-3

MCB-613 after a heart attack prevented the scar and maladaptive repair of heart tissue that can lead to heart failure.

From The Labs

It’s Heart Month!

February 27, 2020February 27, 2020 cardiac fibroblasts, Cardiac regeneration, heart failure, Heart month, heartbeat, Research

From the Labs wraps up Heart Month highlighting a selection of posts about heart-related research at Baylor. The following articles posted in 2019 reveal novel

From The Labs

Image of the Month: cardiac fibroblasts

November 5, 2019November 5, 2019 cardiac fibroblasts, heart attack, heart failure, Hippo pathway, LATS 1/2, Research

This Image of the Month features the cardiac fibroblast, a cell that is central to heart failure, the leading cause of mortality in the U.S.

From The Labs

Tapping on the healing capacity of the heart

January 5, 2018February 5, 2018 Heart disease and regeneration, heart failure, Hippo pathway, injured heart, mouse model, regeneration

If your skin is injured, it can heal itself. If you lose blood, your body makes more. If a lobe is removed from a mouse

From The Labs

How Gata4 helps mend a broken heart

August 14, 2017February 2, 2018 Cardiac regeneration, cardiomyocytes, fibroblasts, fibrosis, Gata4, heart attack, heart failure, scar tissue, tissue reprograming

During a heart attack, blood stops flowing into the heart; starved for oxygen, part of the heart muscle dies. The heart muscle does not regenerate;