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heart failure

From The Labs 

The circadian clock in heart failure

February 3, 2022February 3, 2022chronotherapy, circadian clock, fat metabolism, heart failure, obesity paradox, Research, Rev-erbα/β, sugar metabolism

Disrupting the rhythm of molecular clock protein Rev-erbα/β leads to heart failure in animal models.

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From The Labs 

Innovative approach brings cell-reprogramming therapy for heart failure closer to reality

January 6, 2022January 7, 2022cardiomyocyte, cell reprogramming, endothelial cell, fibroblast, heart failure, Research

A new cell reprogramming strategy can change large scar tissue in rat hearts into working muscle.

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From The Labs 

New research moves novel gene therapy for heart failure closer to the clinic

July 20, 2021July 20, 2021cardiomyocytes, gene therapy, heart attack, heart failure, heart repair, Hippo pathway, Research

Knocking down the Hippo signaling pathway in pig cardiomyocytes after a heart attack, resulted in heart tissue renewal and improved function.

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From The Labs 

MCB-613 helps the heart heal itself after a heart attack

December 17, 2020December 17, 2020heart attack, heart failure, heart repair and regeneration, MCB-613, Research, SRC-3

MCB-613 after a heart attack prevented the scar and maladaptive repair of heart tissue that can lead to heart failure.

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From The Labs 

It’s Heart Month!

February 27, 2020February 27, 2020cardiac fibroblasts, Cardiac regeneration, heart failure, Heart month, heartbeat, Research

From the Labs wraps up Heart Month highlighting a selection of posts about heart-related research at Baylor. The following articles posted in 2019 reveal novel

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Cardiofibroblasts Martin FTL
From The Labs 

Image of the Month: cardiac fibroblasts

November 5, 2019November 5, 2019cardiac fibroblasts, heart attack, heart failure, Hippo pathway, LATS 1/2, Research

This Image of the Month features the cardiac fibroblast, a cell that is central to heart failure, the leading cause of mortality in the U.S.

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From The Labs 

Tapping on the healing capacity of the heart

January 5, 2018February 5, 2018Heart disease and regeneration, heart failure, Hippo pathway, injured heart, mouse model, regeneration

If your skin is injured, it can heal itself. If you lose blood, your body makes more. If a lobe is removed from a mouse

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From The Labs 

How Gata4 helps mend a broken heart

August 14, 2017February 2, 2018Cardiac regeneration, cardiomyocytes, fibroblasts, fibrosis, Gata4, heart attack, heart failure, scar tissue, tissue reprograming

During a heart attack, blood stops flowing into the heart; starved for oxygen, part of the heart muscle dies. The heart muscle does not regenerate;

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From the Labs Image of the Month

From The Labs Image of the Month From the Labs: A selection of From the Labs Images of the Month on display in the A Hallway at Main Baylor.

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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