From The Labs Archives - Page 39 of 99 - Baylor College of Medicine Blog Network

The bone microenvironment ‘empowers’ cancer cells to become metastatic

May 18, 2021 bone microenvironment, Breast Cancer, EZH2, Metastasis, Prostate Cancer, Research

The bone microenvironment prompts changes in breast cancer cells that help them escape treatment and become more invasive.

From The Labs

The Cardiovascular Research Institute 8th Annual Symposium

May 14, 2021 aortic aneurysms, atherosclerosis, atrial fibrillation, COVID, CVRI, heart disease, Research, symposium

Review the symposium highlights, visit the virtual poster session and meet the winners of the first Dr. Mark L. Entman Award for Excellence in Cardiovascular Education.

From The Labs

Novel marker identifies cells that generate new neurons throughout life

May 11, 2021 BASP-1, brain regeneration, NEURAL STEM CELLS, NSC-6, Research

Membrane-bound BASP-1 protein is a possible biomarker of neural stem cells that would allow the study of adult human neurogenesis.

From The Labs

In a cell-eat-cell world calcium ions regulate exposure of ‘eat-me’ signal in necrotic cells

May 6, 2021 C. elegans, calcium ions, necrosis, neurons, phagocytosis, phosphatidylserine, Research

New insights into the process of necrosis suggest that modulating the ‘eat-me’ signal may help reduce the toxic effects of cell death.

From The Labs

Image of the Month: Brain of a mouse model of Huntington’s Disease

May 4, 2021 Alzheimer's, Huntington disease, Image of the month, mouse model, Parkinson disease, Research

This confocal microscopy image shows a section of the brain of a mouse model of Huntington’s disease, with the astrocytes in green and cell nuclei in blue.

From The Labs

Fasting lowers blood pressure by reshaping the gut microbiota

April 29, 2021 animal model, bile acids, fasting, gut microbiota, Hypertension, Research

For the first time researchers show that intermittent fasting can reduce hypertension by reshaping the gut microbiota in an animal model.

From The Labs

Focused on the Heart — Novel mouse model of myotonic dystrophy displays reversible cardiac disease features of the condition

April 27, 2021 alternative splicing, arrhythmias, cardiac function, DM1, DMPK gene, mouse model, myotonic dystrophy, Research

This model of DM1 allows researchers to both focus on cardiac mechanisms of the disease and to expand therapeutics to target the heart.

From The Labs

A new mechanism of cisplatin resistance in cancer, and how to reverse it

April 22, 2021 ACTL6A, cancer resistance to therapy, cisplatin, DNA repair, epigenetic chromatin remodeling, panobinostat, Research

ACLT6A overexpression confers cancer cells resistance to cisplatin, and researchers found a way to reverse it.

From The Labs

POT1 gene mutation predisposes to glioma and affects survival in a sex-specific manner

April 20, 2021 Cancer, Glioma, POT1, Research, tumor immune infliltration

Researchers found gender differences in murine glioma lacking the gene Pot1, including survival, immune response, telomere length and DNA markers.

From The Labs

Selecting the right deconvolution method just got easier

April 15, 2021 analysis of complex cell populations, deconvolution methods, Research, RNA-seq

Extensive evaluation of existing deconvolution methods produced guidelines that scientists can use to determine the method that optimally fits their needs.