Research Archives - Page 22 of 84 - Baylor College of Medicine Blog Network

Microbiome’s link to severe graft-versus-host disease suggests potential treatment

February 28, 2023 bone marrow transplant, GVHD, iron chelator, microbiome, oxygen, Research

This is one of the first studies to provide an explanation and a potential solution for the imbalance in the gut microbiome that exacerbates GVHD.

From The Labs

Metastatic cancer cells reveal potential vulnerabilities with implications for therapy

February 23, 2023 metastatic cancer, molecular pathways, molecular subtypes, Research

This study identified molecular pathways that are common to many different metastatic cancers, regardless of tumor origin.

From The Labs

How to compensate for loss of gene function? Think alternative splicing

February 21, 2023 alternative slicing, gene duplication, MBNL gene, Myotonic Dystrophy Type 1, paralog gene, Research

Researchers uncovered new insights into a little studied biological mechanism that impacts Myotonic Dystrophy Type 1 severity and also is applicable to other diseases.

From The Labs

Better understanding of craniofacial birth defects opens new roads for regenerative medicine

February 16, 2023 craniofacial development, microRNA, Research

The findings could lead to strategies to generate healthy cells to repair craniofacial defects in human patients.

A person sitting on a dock at sunset with their knees pulled up to their head.

From The Labs

Altered gut microbiome and its products promote endometriosis in animal model

February 9, 2023 diagnostics, endometriosis, gut microbiome, microbiome metabolites, Research, treatment

The findings open the door to explore novel therapies and diagnostic tools for this undertreated condition.

A collage of microscopic images of different human cells.

From The Labs

Entanglement within a (transcriptional) bubble explains finely tuned regulation of gene expression

February 7, 2023 enhancer-promoter interactions, entanglement, gene expression, Research, transcriptional bubble

Researchers discovered that transcription of enhancers and promoters is interdependent and propose a mechanism to explain it.

A drain pipe coming out of a wall, spilling water onto the ground.

From The Labs

Sensitive, rapid tests help to ID estrogen-disrupting chemicals in the environment

February 1, 2023 environmental contaminants, estrogen-disrupting chemicals, Microscopy, Research, test for contaminants

The new assays have increased sensitivity and allow for the study of a wide range of biological responses in a single experiment.

From The Labs

Breakthrough epigenetic study can improve the power to predict disease risk

January 31, 2023 CoRSIVs, disease risk, DNA methylation, epigenetics, epigenome-wide association study, EWAS, Research

The researchers hope their approach will have transformative effects in the field of epigenetic epidemiology.

From The Labs

Ataxia mutant protein uses distinct partners to drive toxicity in different brain cells

January 24, 2023 attaxia, ATXN1, capicua, neurodegenerative disorders, Research, SCA1

This study proposes a mechanism for the differential vulnerability of brain cells and regions to toxic mutant proteins.

From The Labs

State of the Lester and Sue Smith Breast Center and breast cancer research

January 19, 2023 animal cancer models, Breast Center, cancer immunology, drug development, drug repurposing, Metastasis, patient care, Research

Interim director Dr. Xiang “Shawn” Zhang sat down with From the Labs to provide an update on this multidisciplinary center dedicated to breast cancer research and patient care.