bone marrow transplant Archives - Baylor College of Medicine Blog Network

Inflammation in the gut leaves long-term marks on intestinal stem cells that affect their response to future challenges.

A graphic illustration of a family that appear as silhouettes filled with germs.

From The Labs

Can changing the gut microbiome alter the course of a disease?

October 24, 2023 bone marrow transplant, butyrate, clinical trial, dietary intervention, graft-versus-host disease, gut microbiome, potato starch, Research

A simple, safe dietary intervention has an effect on the gut microbiome and metabolites in these patients.

From The Labs

Microbiome’s link to severe graft-versus-host disease suggests potential treatment

February 28, 2023 bone marrow transplant, GVHD, iron chelator, microbiome, oxygen, Research

This is one of the first studies to provide an explanation and a potential solution for the imbalance in the gut microbiome that exacerbates GVHD.

Microscopy image of purple leukemia cells amongst healthy pink cells

From The Labs

Promising approach to mitigate complications of leukemia treatment

October 6, 2022 alloimmune defense receptor, bone marrow transplant, CAR T cells, GvH disease, leukemia, leukemia treatment complications, Research

The findings support further assessing this approach to treat aggressive blood cancers and ultimately improve outcomes in patients.

From The Labs

Waking up sleeping beauty – persistent IFN-gamma awakens and activates stem cells via BST2

January 21, 2021 blood stem cells, bone marrow transplant, BST2, E-selectin, homing, IFN, Infectious diseases, Research

The researchers show that persistent IFNγ mediates the exhaustion of blood stem cells via BST2 expression.

From The Labs

“Off-the-shelf” cells are safe and effective to treat viral infections

September 29, 2017 BK virus, bone marrow transplant, Epstein-Barr virus, HHV-6 virus, Immunotherapy, viral inection

A bone marrow transplant can be a life-saving treatment for patients with certain cancers and other serious illnesses that have not responded to conventional chemotherapies.