From mouse model to human; serendipity leads to human genetic diagnosis
When Dr. Huda Zoghbi and her colleagues were investigating the role protein complex ATXN1-CIC plays in the normal development of the mouse brain they did not
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Neuroscience
Big data, brain science and mental health care
The Atlantic recently ran a fascinating article about improving the effectiveness of psychotherapy by using big data to inform practice. In it, the author notes that there
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How the brain remembers fearful experiences
Dr. Daoyun Ji drives to his lab every morning. If asked, he can easily recall the route he takes, “but, what are the brain signals
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Juvenile Batten disease, a problem with cellular waste management
Like a large dynamic city, a cell carries out many activities that generate waste. Waste needs to be disposed of properly in order for the
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Image of the Month: Neuron-muscle synapses in the fruit fly
Certain human gene variants of ATAD3A can cause rare neurological syndromes characterized by global developmental delay, low muscular tone and visual, neurological and heart problems. The
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Small brain region linked to nicotine addiction plays a major role in the control of appetite
[See video beolow] Researchers studying the mystery of how the brain controls appetite have brought into play a small region of the brain, the basal
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'Leaky calcium' gene linked to sudden cardiac death in epilepsy
[See video below] Epilepsy is an extremely common disorder affecting people of all ages, from infants through teenagers to older adults. One of the most
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Image of the Month: Neurons in the lab
Mouse neurons in the lab weave a network of connections through which the cells transmit electrical impulses. These cells represent a valuable model in which to
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Primate study sheds light on human developmental disorders
We are now closer to better understanding brain disorders such as autism and schizophrenia. In a recent paper published in Nature, scientists have elucidated the
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A new experimental system sheds light on how memory loss may occur
Two interconnected brain areas – the hippocampus and the entorhinal cortex – help us to know where we are and to remember it later. It
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