Dr. Huda Zoghbi named the 2022 Kavli Prize Laureate in neuroscience
Dr. Zoghbi is being recognized for two discoveries – ATAXIN1, the gene responsible for spinocerebellar ataxia 1, and MECP2, the gene responsible for Rett syndrome.
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ataxia
Fine-tuning deep brain stimulation plus exercise restore movement in ataxia
A precise combination of DBS and exercise rescued and maintained limb coordination and stepping in mice without further stimulation.
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Regulating gene regulatory regions offers a novel mechanism to control ATXN1 levels
Researchers identified a novel mechanism that regulates ATXN1 levels and reduces SCA1 symptoms in animal model.
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Image of the Month: SCA1-like neurodegeneration
In a mouse model of spinocerebellar ataxia type 1 (SCA1), mice carrying mutant Pumilio1 genes develop progressive motor deficits and cerebellar degeneration. Studies conducted by the
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