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ataxia

From The Labs

Dr. Huda Zoghbi named the 2022 Kavli Prize Laureate in neuroscience

June 2, 2022June 2, 2022 ataxia, Kavli Prize in neuroscience, Research, Rett Syndrome

Dr. Zoghbi is being recognized for two discoveries – ATAXIN1, the gene responsible for spinocerebellar ataxia 1, and MECP2, the gene responsible for Rett syndrome.

From The Labs

Fine-tuning deep brain stimulation plus exercise restore movement in ataxia

April 6, 2021April 6, 2021 ataxia, deep brain stimulation, Purkinje cells, Research

A precise combination of DBS and exercise rescued and maintained limb coordination and stepping in mice without further stimulation.

From The Labs

Regulating gene regulatory regions offers a novel mechanism to control ATXN1 levels

August 27, 2020August 27, 2020 ataxia, ATXN1, balance problems, gene regulation, microRNA, movement problems, Research, SCA1

Researchers identified a novel mechanism that regulates ATXN1 levels and reduces SCA1 symptoms in animal model.

From The Labs

Image of the Month: SCA1-like neurodegeneration

May 1, 2018May 1, 2018 ataxia, mouse model, Neurodegeneration, pumilio, Purkinje cells, Research, spinocerebellar ataxia type 1

In a mouse model of spinocerebellar ataxia type 1 (SCA1), mice carrying mutant Pumilio1 genes develop progressive motor deficits and cerebellar degeneration. Studies conducted by the

From the Labs: Neural connections in the visual pathway of the brain