mouse model Archives - Baylor College of Medicine Blog Network

GlyNAC supplementation extends life span in mice

March 8, 2022 Aging, glutathione, GlyNAC, hallmarks of aging, mitochondrial deficiency, mouse model, oxidative stress, Research

GlyNAC – a combination of precursors of the natural antioxidant glutathione – can increase lifespan and improve multiple key age-associated defects in mice.

From The Labs

Glial cells help mitigate neurological damage in Huntington’s disease

June 24, 2021 brain protection, fruit fly model, glia cells, Huntington’s disease, mouse model, Research, synapse genes

Research with human samples and mouse and fruit fly models opens a window into the brain’s protective responses in Huntington’s disease.

From The Labs

Image of the Month: Brain of a mouse model of Huntington’s Disease

May 4, 2021 Alzheimer's, Huntington disease, Image of the month, mouse model, Parkinson disease, Research

This confocal microscopy image shows a section of the brain of a mouse model of Huntington’s disease, with the astrocytes in green and cell nuclei in blue.

From The Labs

Focused on the Heart — Novel mouse model of myotonic dystrophy displays reversible cardiac disease features of the condition

April 27, 2021 alternative splicing, arrhythmias, cardiac function, DM1, DMPK gene, mouse model, myotonic dystrophy, Research

This model of DM1 allows researchers to both focus on cardiac mechanisms of the disease and to expand therapeutics to target the heart.

From The Labs

A steady supply of sugar is good news for colorectal cancer

March 28, 2019 APC gene, Colorectal Cancer, FASN, fructose, KHK, mouse model, Research, sweet drinks

The current thought is that sugar is harmful to our health mainly because consuming too much can lead to obesity. Research shows that obesity increases

From The Labs

The dark side of antibiotic ciprofloxacin

July 25, 2018 antibiotics, aorta tears and ruptures, aortic aneurysms and dissections, ciprofloxacin, extracellular matrix, fluoroquinolones, mouse model, Research

UPDATE: A few months after this article was posted, the work by Baylor researchers has begun to have international impact. Read the details here. The use

From The Labs

Image of the Month: SCA1-like neurodegeneration

May 1, 2018 ataxia, mouse model, Neurodegeneration, pumilio, Purkinje cells, Research, spinocerebellar ataxia type 1

In a mouse model of spinocerebellar ataxia type 1 (SCA1), mice carrying mutant Pumilio1 genes develop progressive motor deficits and cerebellar degeneration. Studies conducted by the

From The Labs

Two is better than one, to improve brain function on a mouse model of Alzheimer’s disease

April 24, 2018 Alzheimer's Disease, amyloid-beta, mouse model, mTOR, Research

Many of the therapies that are currently being developed to treat Alzheimer’s disease focus on reducing the levels of amyloid-beta, a small protein that is

From The Labs

Mouse model helps solve 15q13.3 microdeletion puzzle

March 22, 2018 15q13.3 microdeletion syndrome, dendritic spines, mouse model, neurodevelopmental disorder, OTUD7A, Research

Individuals with a complex neurological condition called 15q13.3 microdeletion syndrome are missing a small piece of chromosome 15 that usually contains six genes. Although this

From The Labs

Tapping on the healing capacity of the heart

January 5, 2018 Heart disease and regeneration, heart failure, Hippo pathway, injured heart, mouse model, regeneration

If your skin is injured, it can heal itself. If you lose blood, your body makes more. If a lobe is removed from a mouse

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