lysosomes Archives - Baylor College of Medicine Blog Network

Brain sphingolipid metabolism is closely involved in Gaucher disease

July 19, 2022 Gaucher disease, glia, glucosylceramide, lipid metabolism, lysosomes, neurodegenerative disease, neurons, Parkinson's Disease, Research, sphingolipid

Disruption of sphingolipid metabolism led to neurodegeneration in animal models, revealing a new molecular path to Gaucher’s disease.

From The Labs

Talking about aging, lysosomes have something to say

June 14, 2022 Aging, C. elegans, fatty acid signaling, Longevity, lysosomes, Research

The new findings help us understand how longevity is regulated at a whole organism level.

From The Labs

New insights into the fate of dying cells

May 10, 2022 autophagy, C. elegans, CED-1, dying cells, DYN-1, lysosomes, phagocytosis, Research

The Zhou lab reveals a new player in the elimination of dying cells and identifies a mechanism for the process.

From The Labs

Image of the Month: Art meets science to visualize the fruit fly’s brain

April 2, 2019 ALS, autophagy, fruit fly, Lou Gehrig's disease, lysosomes, proteasome, rare disease, reseach, ubiquilin

Studying the brain of the fruit fly helps understand the human brain, both in health and disease. Working in the lab of

From The Labs

Understanding the cell waste disposal problems in Lou Gehrig’s disease

March 12, 2019 ALS, Alzheimer's Disease, autophagy, Drosophila, fruit fly, Lou Gehrig's disease, lysosomes, proteasome, Research, ubiquilin

Building up cellular waste is bad news for cells, and particularly for neurons. Such excessive build up can lead to neurological conditions, as is the

From The Labs

Tuberous sclerosis: it’s not all about mTORC1

February 28, 2019 glycogen, lysosomes, mTORC1, Research, TSC, tuberous sclerosis

mTORC1, a protein complex that regulates cell metabolism, has long been considered the major driving force behind tuberous sclerosis. New experimental evidence, however, is challenging