Ana Rodríguez, Author at Baylor College of Medicine Blog Network

Fighting back lymphoma resistance to treatment

March 15, 2018 cell and gene therapy, Clinical Trials, EBV-specific T cells, Epstein-Barr virus, Hodgkin's Lymphoma, lymphoma, Research, TGFβ

T cell therapies have demonstrated encouraging results and benefits in patients with lymphoma resistant to chemotherapy, but, despite these advances, a large number of patients

From The Labs

Identical twins share more than identical genes

March 13, 2018 cancer risk, epigenetics, identical twins, Research, supersimilarity

For decades, researchers have studied genetically identical twins to estimate what proportion of disease risk is determined by one’s genes. This approach should be reevaluated,

From The Labs

Searching for targets for ependymoma chemotherapy

March 8, 2018 Chemotherapy, childhood brain tumor, ependymoma, epigenomisc, Genomics, Research

From a clinical perspective, the treatment for ependymoma – the third most common childhood brain tumor – has changed little over the last 20 years.

From The Labs

Aminode lets you do in less than a second what used to take a week

March 6, 2018 Aminode, disease-causing mutation, evolutionary relationships, genetic disease, Research

On his first year at Rice University, Kevin Chang, now a senior cognitive sciences major and ecology and evolutionary biology minor, knocked on many doors, including

From The Labs

Image of the Month: Repairing rotavirus-damaged intestinal cells

March 1, 2018 gastroenteritis, intestinal stem cells, Mary Estes, Norovirus, Research, rotavirus

When rotavirus infects and damages intestinal cells, the small intestine fails to absorb nutrients and diarrhea develops. Rotaviruses and noroviruses are the major cause of

From The Labs

Bacteria can have a ‘sweet tooth,’ too

February 27, 2018 C. difficile, dietary sugar, food additive, hospital-acquired infections, superbug, trehalose

Clostridium difficile infections have always been a problem in hospitals, but during the last 15 years they have become the most common cause of hospital-acquired

From The Labs

Uncovering the secrets of the sooty mangabey’s resistance to SIV

February 22, 2018 AIDS, AIDS resistance, Genome Sequencing, HIV, SIV, sooty mangabey

Simian immunodeficiency virus (SIV) infection in macaques behaves in a similar way as infection by human immunodeficiency virus (HIV) in humans, progressing into acquired immunodeficiency

From The Labs

How disrupting mitochondria genes can lead to neurodegeneration

February 20, 2018 idh3a, mitochondria, Neurodegeneration, neurological disease, neurotransmission, synapses

Years back, the Bellen lab identified many mutations in genes of the mitochondria, the energy generators of the cell. Among them was a mutation in

From The Labs

G-quadruplex helps breast cancer survive

February 15, 2018 alternative splicing, Breast Cancer, CD44, G-quadruplex

For breast cancer, expressing the protein CD44s, instead of CD44v, has a survival advantage. And one of the goals of Dr. Chonghui Cheng lab is to

From The Labs

A new approach to potentially treat Huntington’s disease

February 13, 2018 autophagy, huntingtin, Huntington’s disease, lysosome storage disorder, NCT-504, PIP4Kgamma, PIP4Kγ

In Huntington’s disease, a single faulty gene called huntingtin causes a progressive breakdown of nerve cells in the brain and severe physical and neurological damage