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genomic structural variation

From The Labs

Rearranging genomic structure rewires gene control in cancer

November 14, 2019November 14, 2019Cancer, cancer genetics, Cancer Genome Atlas, DNA methylation, epigenetics, genomic structural variation, immune infiltration, Research

Widespread DNA damage is common in the cancer genome. Understanding the mechanisms that lead to it is of great interest to cancer physicians and scientists

From The Labs

Together, big data, bench science and genome-wide diagnostics predict genomic instability that can lead to disease

August 7, 2018August 7, 2018Alu elements, bench science, BigData, copy number variation, genome-wide diagnostics, genomic structural variation, Research

They are the most common repeated elements in the human genome; more than a million copies are scattered among and between our genes. Called Alu

From the Labs: A closer look at tertiary lymphoid structures. Image courtesy of M. Zelazowski/ P. Castro/Baylor’s Human Tissue Acquisition & Pathology (HTAP) Core.