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A microscopic view of prostate cancer. It appears as a field of hazy pink and white with splotches of purple indicating cancer cells.

A novel strategy to suppress prostate cancer growth

October 26, 2022November 3, 2022 androgen receptor, castration therapy, COP1, Gata2, Prostate Cancer, Research, treatment resistance

The researchers took a close look into what drives the growth of advanced tumors that have become resistant to standard castration therapy.

From The Labs

Targeting MAPK4 emerges as a promising therapy for prostate cancer

February 23, 2021February 23, 2021 Akt pathway, androgen receptor, cancer therapy, castration-resistant prostate cancer, MAPK4, Prostate Cancer, Research

Inhibiting MAPK4 simultaneously inactivated both androgen receptor and AKT and stopped cancer growth in animal models.

From The Labs

New oncogene MNX1 contributes to higher incidence of prostate cancer among African American men

October 12, 2016 African American men, AKT, lipid metabolism, oncogene MNX1, Prostate Cancer, testosterone

Genetic factors can explain, at last in part, the higher incidence of prostate cancer among African American men compared with men of other ethnic groups.

Momentum

Prostate cancer: What you need to know

September 14, 2016September 9, 2019 Allison Mickey, Blue Cure Foundation, Cancer, Community, Dr. Jennifer Taylor, Events, Healthcare, Houston, Men's Health, Prostate Cancer, Urology

During the month of September, Baylor College of Medicine will be partnering with the Blue Cure Foundation for its annual prostate cancer awareness campaign, Light

From The Labs

Altered metabolism in castration-resistant prostate cancer may point to new therapies

September 13, 2016June 23, 2020 altered metabolism, Cancer, castration-resistant, hexosamine biosynthetic pathway, metabolism, Prostate Cancer, therapeutic target

Advanced prostate cancer is usually treated by removing androgen, the male hormone that helps it grow. Although initially effective, this treatment often leads to the

From The Labs

Mouse model shows that Notch activation can drive metastatic prostate cancer

August 23, 2016May 4, 2018 Metastasis, metastatic prostate cancer, mouse model, Notch signaling pathway, Prostate Cancer, Pten gene, Research

Nearly 200 thousand men are diagnosed with prostate cancer every year. Most of the deaths associated with prostate cancer occur in advanced stages of the

Momentum

Baylor College of Medicine lights up blue in honor of Prostate Cancer Awareness Month

September 4, 2015October 7, 2016 Blue Cure Foundation, Cancer, Community, Dan L. Duncan Cancer Center, Events, Glenna Vickers, Healthcare, Houston, Light it up blue, Men's Health, Prostate Cancer

September officially kicks off National Prostate Cancer Awareness Month, and in a show of support for increased awareness, education, research and clinical advances, the Baylor

From The Labs

Coactivator forges pathway for survival of metastatic prostate cancer

March 16, 2015

By Ruth SoRelle, M.P.H. A steroid receptor coactivator (SRC-2) drives the metabolic mechanism that allows prostate cancer not only to grow but also to spread

From The Labs

Blocking a coactivator may be answer to androgen-resistant prostate cancer

November 4, 2014

By Ruth SoRelle, M.P.H. Treating advanced prostate cancer with drugs that block androgens or male hormones can result in resistance to the drugs, and is

Two slides showing breast cancer cells as blue or green dots on a blue background.

From The Labs

A potential strategy to control MAPK4-dependent cancer growth

August 8, 2023August 8, 2023 AKT, cancer growth, lung cancer, MAPK4, PDK1, Prostate Cancer, Research, triple-negative breast cancer

This study has advanced our understanding of the molecular mechanisms underlying the tumor-promoting activity of MAPK4.