In Memoriam: Bert W. O’Malley, M.D.
During his decades-long career, Dr. Bert O’Malley changed our understanding of endocrinology in a fundamental way.
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SRC-3
Baylor researchers awarded the National Academy of Sciences 2023 Cozzarelli Prize in Biomedical Sciences
The research warrants continuing investigations to translate the findings into a novel, more effective and longer-lasting cancer therapy.
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Eliminating gene SRC-3 in immune cells triggers effective long-lasting anti-cancer response
The findings in animal models warrant continuing investigations to develop a novel, more effective and longer-lasting cancer therapy.
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SRC-3 is a key regulator of the 12-hour clock
Altered 12-hour cycles have been associated with human diseases and hundreds of genes have been identified that are activated in 12-hour cycles.
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The multitasking nature of SRC-3
SRC-3 not only influences steroid hormone function and gives a heads up for aggressive human breast cancer, it also regulates immune T cells.
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MCB-613 helps the heart heal itself after a heart attack
MCB-613 after a heart attack prevented the scar and maladaptive repair of heart tissue that can lead to heart failure.
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This is what the Warburg pathway can do for breast cancer growth
To generate energy from glucose, cells can use one of two pathways. One of them takes place in the mitochondria, energy-producing structures inside cells, and
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New class of small molecule, SI-2, can drug the ‘undruggable’ steroid receptor coactivator-3
By Ana María Rodríguez, Ph.D. Steroid receptor coactivator-3, which is well-known for its role in cancer formation and proliferation, is usually considered ‘undruggable’ because this nuclear
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