SRC-3 Archives - Baylor College of Medicine Blog Network

Baylor researchers awarded the National Academy of Sciences 2023 Cozzarelli Prize in Biomedical Sciences

March 19, 2024 Awards, Breast Cancer, Cozzarelli Prize, National Academy of Sciences, PNAS, Prostate Cancer, Research, SRC-3

The research warrants continuing investigations to translate the findings into a novel, more effective and longer-lasting cancer therapy.

From The Labs

Eliminating gene SRC-3 in immune cells triggers effective long-lasting anti-cancer response

June 8, 2023 Breast Cancer, cancer treatment, Prostate Cancer, Research, SRC-3, Tregs, tumor microenvironment

The findings in animal models warrant continuing investigations to develop a novel, more effective and longer-lasting cancer therapy.

From The Labs

SRC-3 is a key regulator of the 12-hour clock

March 10, 2022 12-hour biological clock, chronotherapeutics, circadian rhythm, circatidal rhythm, Research, SRC-3, tides, XBP1

Altered 12-hour cycles have been associated with human diseases and hundreds of genes have been identified that are activated in 12-hour cycles.

From The Labs

The multitasking nature of SRC-3

March 23, 2021 Breast Cancer, cancer survival, immune system, Research, SRC-3, steroid hormone, T regulatory cells

SRC-3 not only influences steroid hormone function and gives a heads up for aggressive human breast cancer, it also regulates immune T cells.

From The Labs

MCB-613 helps the heart heal itself after a heart attack

December 17, 2020 heart attack, heart failure, heart repair and regeneration, MCB-613, Research, SRC-3

MCB-613 after a heart attack prevented the scar and maladaptive repair of heart tissue that can lead to heart failure.

From The Labs

This is what the Warburg pathway can do for breast cancer growth

May 17, 2018 Breast Cancer, glucose metabolism, Metastasis, PFKFB4, Research, SRC-3, Warburg pathway

To generate energy from glucose, cells can use one of two pathways. One of them takes place in the mitochondria, energy-producing structures inside cells, and

From The Labs

New class of small molecule, SI-2, can drug the ‘undruggable’ steroid receptor coactivator-3

June 16, 2016 Cancer, drugs, SI-2, SRC-3, steroid receptor, steroid receptor coactivator

By Ana María Rodríguez, Ph.D. Steroid receptor coactivator-3, which is well-known for its role in cancer formation and proliferation, is usually considered ‘undruggable’ because this nuclear