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Tuesday, January 26, 2021
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Author: Ana Rodríguez

From The Labs 

Connecting the dots between lactating mother’s diet, milk composition, microbiome and benefits of mother’s milk

January 26, 2021January 26, 2021 Ana Rodríguez 0 Comments Breastfeeding, diet, HMO, metabolic health, milk microbiome, Research

This study reports the first evidence that the mother’s diet while breastfeeding can shape the profile of HMOs, a type of food for microbes, which in turn modifies the functional abilities of the milk microbiome.

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From The Labs 

Waking up sleeping beauty – persistent IFN-gamma awakens and activates stem cells via BST2

January 21, 2021January 21, 2021 Ana Rodríguez 0 Comments blood stem cells, bone marrow transplant, BST2, E-selectin, homing, IFN, Infectious diseases, Research

The researchers show that persistent IFNγ mediates the exhaustion of blood stem cells via BST2 expression.

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From The Labs 

Study of spliceosome-targeting cancer therapies reveals an overlooked role of mis-spliced RNAs themselves

January 19, 2021January 19, 2021 Ana Rodríguez 0 Comments apoptosis, cancer treatment, Immunotherapy, Research, RNA splicing, Spliceosome-targeting therapies, triple-negative breast cancer

Endogenous mis-spliced RNA in tumor cells mimics an RNA virus, leading tumor cells to self-destruct as if fighting an infection.

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From The Labs 

BICRA gene variants linked to a neurodevelopmental disorder

January 14, 2021January 14, 2021 Ana Rodríguez 0 Comments BICRA gene, Coffin-Siris syndrome, fruit fly, neurodevelopmental disease, neurodevelopmental disorder, Research, zebra fish

Genetic testing of an undiagnosed condition triggered a study that linked the BICRA to a neurodevelopmental disorder.

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From The Labs 

‘Rule-breakers’ help identify novel gene variants that modify risk of late-onset Alzheimer’s disease

January 12, 2021January 14, 2021 Ana Rodríguez 0 Comments ADSP, APOE, fruit fly, genetic risk, Late-onset Alzheimer’s disease, Research

Using novel methodologies, researchers identified 216 new gene variants, many previously not suspected to play a role in Alzheimer’s disease.

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From The Labs 

Rhesus macaque genome study enhances our understanding of human genetic variation

January 7, 2021January 14, 2021 Ana Rodríguez 0 Comments genetic variation, reference genome, Research, Rhesus macaque

Substantially improved rhesus macaque genome reference assembly helps answer fundamental questions in genetics, cell biology and physiology.

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From The Labs 

The Most Viewed Image of the Month in 2020

January 5, 2021January 5, 2021 Ana Rodríguez 0 Comments AKOX1, Image ofthe month, research myelin, Schwann cells, sciatic nerve

‘Transverse view of the sciatic nerve’ placed on top as the most viewed Image of the Month in 2020.

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From The Labs 

Making strides in tackling osteoarthritis

December 31, 2020December 31, 2020 Ana Rodríguez 0 Comments cartilage, Osteoarthritis, platelet-rich plasma, Research

This study assesses clinically relevant formulations of platelet-rich plasma that can delay osteoarthritis progression and improve pain.

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From The Labs 

From the Labs top five most viewed posts of 2020

December 30, 2020December 29, 2020 Ana Rodríguez 0 Comments Alzheimer's, bile acids, COVID19, Diabetes, fat storage, herpes, Norovirus, Research, scents, top five most viewed posts

During 2020, research news on COVID-19 led the headlines, but significant contributions emerged in other fields as well.

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From The Labs 

Nuclear, not cytoplasmic CELF1, has a stronger role in muscle wasting

December 29, 2020December 29, 2020 Ana Rodríguez 0 Comments alternative splicing, CELF1 and MBNL proteins, DM1, DMPK gene, muscle wasting, myotonic dystrophy, Research

This work is the first to show that the response of muscle to CELF1 overexpression depends on the cellular localization of the protein.

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From the Labs Image of the Month

From The Labs Image of the Month From the Labs kicks off the new year with the most viewed Image of the Month of 2020.

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