A new mechanism of cisplatin resistance in cancer, and how to reverse it
ACLT6A overexpression confers cancer cells resistance to cisplatin, and researchers found a way to reverse it.
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Author: Ana Rodríguez
POT1 gene mutation predisposes to glioma and affects survival in a sex-specific manner
Researchers found gender differences in murine glioma lacking the gene Pot1, including survival, immune response, telomere length and DNA markers.
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Selecting the right deconvolution method just got easier
Extensive evaluation of existing deconvolution methods produced guidelines that scientists can use to determine the method that optimally fits their needs.
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Closer to human – mouse model more accurately reproduces fatty liver disease
A mouse model that closely replicates fatty liver disease can be used to better understand the condition and identify effective therapies.
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Prolonged infection and inflammation drain immune responses as we age
Sustained infection and inflammation wear down the immune system as we age reducing its ability to fight disease.
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Fine-tuning deep brain stimulation plus exercise restore movement in ataxia
A precise combination of DBS and exercise rescued and maintained limb coordination and stepping in mice without further stimulation.
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Image of the Month: Training and neuronal activation in Rett mice
Early physical training triggers more dendritic arbors or cellular projections in hippocampal neurons (red), enhancing their functionality.
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Phages can prevent infection before it happens
Researchers have identified a novel strategy that can eliminate bacteria in a specific location before they cause an infection.
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Research opens new possibilities to improve the lives of girls with Rett syndrome
In a mouse model of Rett syndrome, early intensive training substantially delayed the appearance of symptoms and improved performance.
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The multitasking nature of SRC-3
SRC-3 not only influences steroid hormone function and gives a heads up for aggressive human breast cancer, it also regulates immune T cells.
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