CAR T cell therapy makes strides in tackling Hodgkin lymphoma
Most patients with Hodgkin lymphoma (HL), a type of cancer of immune cells called B lymphocytes, are cured with first-line therapy, but approximately 15 percent
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Author: Ana Rodríguez
Tackling the root cause of treatment resistance in age-related macular degeneration
The leading cause of irreversible blindness in the elderly is an aggressive form of age-related macular degeneration known as choroidal neovascularization (CNV). The projected number
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Image of the Month: Cancer cell clusters
The image of this month shows a cluster of breast cancer tumor cells that was found in the blood of mice bearing the tumor. Researchers
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The N-terminal domain of the androgen receptor is at the heart of its action
Detailed 3-D studies reveal how the androgen receptor is put together as a functional complex that drives prostate cancer.
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Taking a closer look into the tumor microenvironment with nano-radiomics
Nano-radiomics analysis of imaging data assesses changes in the tumor microenvironment that cannot be detected with conventional imaging methods.
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PolyA-miner accurately assesses the effect of alternative polyadenylation on gene expression
PolyA-miner enables scientists to evaluate the contribution of alternative polyadenylation to gene regulation in health and disease.
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New insights into the mediators of patient recovery after CAR T cell immunotherapy
Clinical trial of novel personalized CAR T cell immunotherapy provides clues into what mediated exceptional patient recovery.
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These 300,000 cells can improve our understanding of chronic lung disease
Despite substantial progress in the understandig of pulmonary fibrosis (PF) in laboratory animals, researchers have a limited perspective of the cellular and molecular processes that
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Sorting out cell type-specific molecular barcodes
In the last 10 years, scientists generated thousands of whole genome bisulfite sequencing (WGBS) data sets costing millions of dollars, yet were unable to appreciate
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No NELL2, no sperm motility. Novel protein is essential for male fertility
Newly produced spermatozoa within the testis are not fully functional until they mature in the epididymis, a duct that helps to transport and store sperm.
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